Description
Genetics of Human Infertility
Monographs in Human Genetics Series, Vol. 21
Language: EnglishSubjects for Genetics of Human Infertility:
Keywords
Genetics, Andrology, Cytology, Gynecology, Chromosomes, Fertility
Publication date: 09-2017
188 p. · Hardback
188 p. · Hardback
Description
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Infertility affects more than one in ten couples worldwide and is related
to highly heterogeneous pathologies sometimes only discernible in the germ
line. Its complex etiology often, but not always, includes genetic factors
besides anatomical defects, immunological interference, and environmental
aspects. Nearly 30% of infertility cases are probably caused only by
genetic defects. Thereby experimental animal knockout models convincingly
show that infertility can be caused by single or multiple gene defects.
Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods.
This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.
Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods.
This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.
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