Description
CRISPR-Cas Systems, 2013
RNA-mediated Adaptive Immunity in Bacteria and Archaea
Coordinators: Barrangou Rodolphe, van der Oost John
Language: EnglishSubject for CRISPR-Cas Systems:
Keywords
Publication date: 01-2015
Support: Print on demand
Publication date: 12-2012
302 p. · 15.5x23.5 cm · Soft-cover
Description
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CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered.
In this book, experts summarize the state of the art in this exciting field.
Discovery and seminal developments in the CRISPR field.- Occurrence, diversity of CRISPR-Cas systems and genotyping implications.- Evolution and classification of CRISPR-Cas systems and Cas protein families.- Regulation of CRISPR-based immune responses.- crRNA Biogenesis.- Distribution and mechanism of the Type I CRISPR/Cas Systems.- Type II – Streptococcus thermophilus.- Type III CRISPR-Cas Systems and the Roles CRISPR-Cas in Bacterial Virulence.- CRISPR-Cas Systems to Probe Ecological Diversity and Host-Viral Interactions.- Roles of CRISPR in regulation of physiological processes.- Applications of the versatile CRISPR-Cas systems.- CRISPRs in microbial community context.
This is the first book in this exciting field
Includes the new CRISPR-Cas systems categorization
Written by the leading experts of the CRISPR research community
Includes supplementary material: sn.pub/extras