Current Developments in Biotechnology and Bioengineering
Bioprocesses, Bioreactors and Controls

Coordinators: Larroche Christian, Sanroman M. Angeles, Du Guocheng, Pandey Ashok

Language: English
Cover of the book Current Developments in Biotechnology and Bioengineering

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Current Developments in Biotechnology and Bioengineering: Bioprocesses, Bioreactors and Controls provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, reviewing industrial biotechnology and bioengineering practices that facilitate and enhance the transition of processes from lab to plant scale, which is becoming increasingly important as such transitions continue to grow in frequency.

Focusing on industrial bioprocesses, bioreactors for bioprocesses, and controls for bioprocesses, this title reviews industrial practice to identify bottlenecks and propose solutions, highlighting that the optimal control of a bioprocess involves not only maximization of product yield, but also taking into account parameters such as quality assurance and environmental aspects.

Industrial Bioprocesses

1. Industrial bioprocesses and the biorefinery concept

2. Omics tools for bioprocess development

3. Cell factories for industrial bioprocesses

4. Enzyme systems for industrial bioprocesses

5. Design and types of bioprocesses

6. Bioprocess engineering and process optimization

7. Microbial bioprocesses

8. Plant cell bioprocesses

9. Animal cell bioprocesses

10. Biofilm bioprocesses

Bioreactors for Industrial Bioprocesses

11. Basics of Bioreactor Design

12. Stirred-Tank Bioreactors

13. Nonmechanically Agitated Bioreactors

14. Packed-bed Bioreactors

15. Membrane Bioreactors

16. Photobioreactors

17. Solid-State Fermentation Bioreactor Fundamentals

18. Bioreactor Development for the Cultivation of Extremophilic Microorganisms

19. Application of Microbioreactors for Bioprocesses

20. Modeling and Control of Bioreactors

21. Scale-up strategies of Bioreactors

Controls of Industrial Bioprocesses

22. Principles of bioprocess control

23. Characterization of industrial bioreactors (mixing, mass and heat transfer)

24. Present status of standard instruments for bioprocess analysis and control

25. Biosensors

26. Real-time Knowledge-Based Systems

Professor Christian Larroche is a graduate in Biochemical Engineering from the INSA, Toulouse, (1979), Docteur-Ingénieur in Organic Chemistry from Paul Sabatier Toulouse 3 University (1982), and Docteur ès Sciences (Ph D) in Biochemical Engineering from Blaise Pascal University (1990). He has strong research interest in the area of applied microbiology and biochemical engineering. His skills are related to biochemical engineering, especially the study and development of special processes for the use of microorganisms. This includes fungal spores production by solid state cultivation and their use as protein (enzyme) reservoir in biotransformations. A special interest in phase transfer phenomena coupled to metabolic engineering has to be noticed. It is applied to the design and optimisation of biotransformations involving hydrophobic compounds and carried out in biphasic liquid-liquid media. These processes are related both to the food and environment (bioremediation) areas. His interests have recently be extended to bioenergy, and he is presently co-ordinator of two French research programs on biohydrogen production by non photosynthetic anaerobic microorganisms grown on complex media.

He is author of about 170 documents, including 75 articles, two patents, 12 book chapters and 18 co-edition of books or journal special issues. He has supervised 10 PhD students and 20 MSc lab works. He is member of SFGP (French Society for Process Engineering) and vice chairman & administrator of IFIBiop, an international network entitled "International Forum on Industrial Bioprocesses". He is head of the department of "Study and Development of Processes involving Microorganisms" of the platform for technological development Biotechnology – Material Engineering of Blaise Pascal University and belongs to the team GePEB (Process engineering, Energetics and Biosystems) of the Institut Pascal in the same university. He has been vice-president of the university in charge of rese

  • Describes industrial bioprocesses based on the reaction media
  • Lists the type of bioreactors used for a specific bioprocess/application
  • Outlines the principles of control systems in various bioprocesses