Fly Models of Human Diseases

1. Fly Models of Human Diseases: Drosophila as a Model for Understanding Human Mitochondrial Mutations and Disease Aditya Sen and Rachel T. Cox 2. Drosophila as a Model for Human Diseases - Focus on Innate Immunity in Barrier Epithelia Peter Bergman, Shiva Seyedoleslami Esfahani and Ylva Engström 3. Drosophila melanogaster as a Model of Muscle Degeneration Disorders Rebecca E. Kreipke, Young V. Kwon, Halyna R. Shcherbata and Hannele Ruohola-Baker 4. Amyotrophic Lateral Sclerosis Pathogenesis Converges on Defects in Protein Homeostasis Associated with TDP-43 Mislocalization and Proteasome-Mediated Degradation Overload Guang Lin, Dongxue Mao and Hugo J. Bellen 5. Mechanisms of Parkinson's Disease: Lessons from Drosophila Victoria L. Hewitt and Alexander J. Whitworth 6. Neurotoxicity Pathways in Drosophila Models of the Polyglutamine Disorders Megan Krench and J. Troy Littleton 7. AxGxE: Using Flies to Interrogate the Complex Etiology of Neurodegenerative Disease Christopher Burke, Kien Trinh, Vidya Nadar and Subhabrata Sanyal 8. Unraveling the Neurobiology of Sleep and Sleep Disorders Using Drosophila Leela Chakravarti, Emilia H. Moscato and Matthew S. Kayser 9. Modeling Human Cancers in Drosophila Masahiro Sonoshita and Ross L. Cagan 10. Stem-Cell-Based Tumorigenesis in Adult Drosophila Steven X. Hou and Shree Ram Singh 11. The Drosophila Accessory Gland as a Model for Prostate Cancer and Other Pathologies Clive Wilson, Aaron Leiblich, Deborah C. I. Goberdhan and Freddie Hamdy 12. Drosophila melanogaster Models of Galactosemia Jennifer M. I. Daenzer and Judith L Fridovich-Keil 13. Drosophila as a Model for Diabetes and Diseases of Insulin Resistance Patricia Graham and Leslie Pick

• Covers all aspects of fly models of human diseases
• Includes contributions from an International board of authors
• Provides a comprehensive set of reviews, covering such topics as cell proliferation, cell differentiation, and biological significance