Heat Shock Proteins in Neuroscience, 1st ed. 2019
Heat Shock Proteins Series, Vol. 20

The book Heat Shock Proteins in Neuroscience provides the most comprehensive review on contemporary knowledge on the role of HSP in signaling pathways relevant to a number of diseases. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding of Neurological Aspects of HSP; Section II, focuses on Aspects of HSP in Neurodegenerative Diseases and Disorders, Section III, emphasizes the importance of HSP in Multiple Sclerosis; Section IV, reviews critical Aspects of HSP in Alzheimer?s Disease and Section V, gives a comprehensive update of the Development of HSP-Based Therapies for Neurological Disorders.  

Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for starters and professionals in the fields of Neurology and Neurosciences, Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

Section I: Neurological Aspects of HSP

Chapter 1. Hsp60 Friend And Foe Of The Nervous System

Antonella Marino Gammazza, Celeste Caruso Bavisotto, Francesca Rappa, Federica Scalia, Everly Conway de Macario,Alberto JL Macario andFrancesco Cappello

Department of Experimental Biomedicine and Clinical Neurosciences

University of Palermo

Palermo, Italy

Chapter 2.Role Of Heat Shock Proteins In Brain Tumors

George A. Alexiou             

Department of Neurosurgery

University Hospital of Ioannina

Ioannina, Greece

Chapter 3.Body Temperature Regulation Determines Immune Reactions And Species Longevity

Ian James Martins

School of Medical Sciences

Edith Cowan University

Western Australia, Australia

Chapter 4.Interaction Between Heat Shock Proteins And Components Of The Plasminogen Activator System In The Central Nervous System

Mario Gonzalez-Gronow and Salvatore V.P izzo

Department of Biological Sciences, Laboratory of Environmental Neurotoxicology

Universidad Católica del Norte

Coquimbo, Chile

And

Department of Pathology

Duke University Medical Center

Durham, USA

Chapter 5. Role Of HSP70 In Plasticity And Memory

Rossana Rosa Porto and Lucas De Oliveira Alvares

Neurobiology of Memory Laboratory

Biophysics Department

Biosciences Institute

Chapter 6.Role Of Heat Shock Proteins (HSP) In Neuroprotection For Ischemic Stroke

Jong Youl Kim, Jong Eun Lee and Midori A. Yenari

Department of Neurology

San Francisco, USA

Section II: Aspects of HSP in Neurodegenerative Diseases and Disorders

Panchanan Maiti and Jayeeta Manna

Department of Psychology

Central Michigan University

Mt. Pleasant, USA

Chapter 8.Molecular Chaperones And Protein Quality Control System In The Canine Model Of Brain Aging And Neurodegenerative Diseases

Romanucci Mariarita and Leonardo Della Salda

Veterinary Pathology Unit, Faculty of Veterinary Medicine

University of Teramo

Teramo, Italy

Chapter 9.Role Of Hsp90 Interacting Molecular Chaperones On Tau And Aß Processing In Alzheimer’s Disease

Department of Pharmaceutical Sciences

Byrd Alzheimer’s Institute, College of Pharmacy

University of South Florida-Health

Section III: Aspects of HSP in Multiple Sclerosis

Chapter 10.Role Of Hsp70 In Multiple Sclerosis: An Overview

Maria Magdalena Barreca and Fabiana Geraci

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies

University of Palermo

Palermo, Italy

Benjamin E. Clarke, Bernadett Kalmar and Linda Greensmith

UCL Queen Square Institute of Neurology

London, UK

Section IV: Development of HSP-Based Therapies for Neurological Disorders

Chapter 12.Therapeutic Drugs And Natural Products: The Effect Of Suppressing Hsps In Brain Tumors

Elif Mertoğlu, Aslıhan Şengelen, Ezgi Kıyga and Evren Önay Uçar

Department of Molecular Biology & Genetics

Istanbul University

Chapter 13.Can HSP Targeted Gene Therapy Be A New Hope for Gliomas?

Evren Önay-Uçar, Aslıhan Şengelen, Elçin Güngör, Elif Mertoğlu, Murat Pekmez and Nazlı Arda

Department of Molecular Biology & Genetics

Istanbul University

Chapter 14.Therapeutic Aspects Of Heat Shock Proteins In Glioma: Cementing The Crevasses Between Bench And Bedside

Y.Rajesh, Utkarsh and Mahitosh Mandal

School of Medical Science and Technology

Indian Institute of Technology

Kharagpur, India

Chapter 15.Engineering Chaperones For Alzheimer’s Disease: Insights From Drosophila Models

Alfonso Martín-Peña and Diego E. Rincon-Limas

Department of Neurology

McKnight Brain Institute

Gainesville, FL

Chapter 16.Role Of HSP In The Treatment Of Internal Dıseases

Ferda Hosgorler, Ozden Yildirim Akan and Pınar Kurçeren Ortan

Division of Neurology

Alsancak Izmir/TURKEY

Dr. Punit Kaur is an expert in onco-proteogenomics, with extensive training and experience in quantitative mass spectrometry imaging, protein chemistry and biomarker discovery. Dr. Kaur’s main research focus is on the use of heat-induced nanotechnology in combination with radiotherapy and chemotherapy in the cancer stem cell therapy. Dr. Kaur has published more than 40 scientific articles, book chapters, and reviews, and currently serves as editorial board member for the European Journal of Cancer Prevention and the Journal of Proteomics and Bioinformatics. Dr. Kaur is an editor of 9 books in the highly successful Heat Shock Proteins book series by Spring

Provides the most comprehensive review of contemporary knowledge on the role of HSP in signaling pathways relevant to a number of diseases

Contains chapters contributed by specialists from key basic and clinical research laboratories at major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world

An important source of reference for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Clinical Psychology, Human Physiology, Zoology, Botany, Biotechnology, Molecular Medicine, Infectious Disease, Pathology and Pharmaceutical Sciences, as well as for researchers involved in Drug Discovery