Kidney Development and Disease, 1st ed. 2017
Results and Problems in Cell Differentiation Series, Vol. 60

Coordinator: Miller Rachel K.

Language: English

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Kidney Development and Disease
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210.99 €

In Print (Delivery period: 15 days).

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Kidney Development and Disease
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Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes.


Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.  

A. Model Systems of Kidney Development and Disease: 
1. Madhu Tapadia   madhu@bhu.ac.in
Co-author: Naveen Gautam gautam.naveen6@gmail.com 
Topic: Drosophila Malpighian Tubule Development

2. Alan Davidson a.davidson@auckland.ac.nz 
Co-author: Richard Naylor
Topic: Zebrafish Nephron Formation

3. Rebecca Wingert rwingert@nd.edu 
Co-author: graduate student
Topic: Zebrafish as a model of kidney disease

4. Kelly McLaughlin kelly.mclaughlin@tufts.edu
Co-author: Shoshoni Caine
Topic: Use of Xenopus frogs to study renal development/repair

B. Cell Renewal, Differentiation and Fate in Nephrogenesis:
5.
Zubaida Saifudeen zubisaif@tulane.edu 
Topic: p53-Energy metabolism directed renewal vs differentiation

6. Peter Hohenstein peter.hohenstein@roslin.ed.ac.uk
Co-author: Derya Ozdemir Derya.Ozdemir@roslin.ed.ac.uk 
Topic: Wilms’ tumors and differentiation (tentative)

7. Leif Oxburgh oxburl@mmc.org 
Co-authors: Deepthi Muthukrishnan, Aaron Brown, Sarah McCarthy, Jennifer Fetting
Topic: Growth factor regulation in the nephrogenic zone

8. Wenzheng Zhang Wenzheng.zhang@uth.tmc.edu
Co-aut
hors: Lihe Chen and Paul Higgins Topic: Development and Diseases of the Collecting Duct 

9. Norman Rosenblum norman.rosenblum@sickkids.ca
Co-authors: Christopher Rowan and Sepideh Sheybani Deloui
Topic: Origin and function of the renal stroma in health and disease

C. Nephron Morphogenesis and Maintenance:
10. Ian Smyth ian.smyth@monash.edu 
Co-author: Kieran Short kieran.short@monash.edu 
Topic: integrating tissue morphology and cellular events during branching morphogenesis in the developing kidney

11. Kimberly Reidy kreidy@montefiore.org 
Topic: Polarity Proteins in Kidney Development and Disease (tentative)

12. Pamela Tran ptran@kumc.edu 
Topic: Cilia in Cystic Kidney Disease

13. Brad Yoder byoder@uab.edu 
Co-authors: Cheng Song song1c@uab.edu 
Kurt A Zimmerman zimmermk@uab.edu 
Topic: Inflammation and Fibrosis in Polycystic Kidney Disease

14.
Ana Sofia Cruz sofiacruzs@gmail.com
Co-authors: Arvind Bhimaraj and Keith Youker
Topic: Endothelial to Mesenchymal Transition in Kidney Fibrosis

Highlights recent advances in the three primary areas of kidney research

Brings together established and young investigators

Written by international experts in the field

Includes supplementary material: sn.pub/extras