Description
Membrane Transporters in Drug Discovery and Development, Softcover reprint of the original 1st ed. 2010
Methods and Protocols
Methods in Molecular Biology Series, Vol. 637
Coordinator: Yan Qing
Language: EnglishSubjects for Membrane Transporters in Drug Discovery and Development:
Keywords
In silico; PCR; bioinformatics; cells; genome; molecular biology; physiology; skeletal muscle
Publication date: 08-2016
Support: Print on demand
365 p. · 17.8x25.4 cm · Hardback
Description
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Studies of membrane transporters have had a great impact on our understanding of human diseases and the design of effective drugs. In Membrane Transporters in Drug Discovery and Development: Methods and Protocols, expert researchers provide practical methodologies of the ongoing research on membrane transporters, considering applications of transporter technologies in drug discovery and development. Chapters include new and useful fields and methodologies, including pharmacogenomics, nutrigenomics, systems biology, bioinformatics, nuclear magnetic resonance (NMR), imaging, and quantitative real-time-PCR. Transporter studies in drug discovery and development for various diseases are discussed, including neuropsychiatric disorders, cardiovascular diseases, ophthalmic diseases, cancer, and diabetes. Composed in the highly successful Methods in Molecular Biology? series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.
Wide-ranging and current, Membrane Transporters in Drug Discovery and Development: Methods and Protocols delivers a collection of practical protocols that can be used immediately in the lab, along with critical surveys of key topics by leading researchers in the field.