Nanotechnology and Regenerative Engineering (2^nd Ed.)
The Scaffold, Second Edition

Nanotechnology and regenerative engineering have emerged to the forefront as the most versatile and innovative technologies to foster novel therapeutic techniques and strategies of the twenty-first century. The first edition of Nanotechnology and Tissue Engineering: The Scaffold was the first comprehensive source to explain the developments in nanostructured biomaterials for tissue engineering, the relevance of nanostructured materials in tissue regeneration, and the current applications of nanostructured scaffolds for engineering various tissues. This fully revised second edition, renamed Nanotechnology and Regenerative Engineering: The Scaffold, provides a thorough update to the existing material, bringing together these two unique areas to give a perspective of the emerging therapeutic strategies for a wide audience.

New coverage includes:

• Updated discussion of the importance of scaffolds in tissue engineering
• Exploration of cellular interactions at the nanoscale
• Complete range of fabrication processes capable of developing nanostructured scaffolds for regenerative engineering
• Applications of nanostructured scaffolds for neural, skin, cardiovascular, and musculoskeletal regenerative engineering
• FDA approval process of nanostructure scaffolds
• Products based on nanostructured scaffolds

Due to the unique and tissue-mimic properties of the nanostructured scaffolds, the past five years have seen a tremendous growth in nanostructured materials for biological applications. The revised work presents the current state-of-the-art developments in nanostructured scaffolds for regenerative engineering.

SECTION I Importance of Scaffolds in Tissue Regeneration. Tissue Engineering: The Therapeutic Strategy of the Twenty-First Century . From Microenvironment to Nanoenvironment: Ultrastructure and Function of . Extracellular Matrix. Functions and Requirements of Synthetic Scaffolds in Tissue Engineering. Microfabrication Techniques in Scaffold Development. SECTION II Effect of Nanostructures on Cellular Responses and Tissue Regeneration. Cell Response to Nanoscale Features and Its Implications in Tissue Regeneration: An Orthopedic Perspective. Surface Modification of Biomaterials at the Nanoscale: Biomimetic Scaffolds for Tissue Engineering Applications. SECTION III Promising Nanofabrication Techniques for Scaffolds to Support Tissue Regeneration. Electrospun Polymeric Nanofiber Scaffolds for Tissue Regeneration. Structure and Mechanical Properties of Electrospun Nanofibers and Nanocomposites. Electrospinning Techniques to Control Deposition and Structural Alignment of Nanofibrous Scaffolds for Cellular Orientation and Cytoskeletal Reorganization. Nanolithographic Techniques in Tissue Engineering. Designer Self-Assembling Peptide Scaffolds for Tissue Engineering and Regenerative Medicine. SECTION IV Applications of Nanostructured Scaffolds in Biology and Medicine. Nanotechnologies to Promote Skin Tissue Regeneration . Nanotechnologies for Neural Tissue Engineering . Nanotechnologies for Cardiovascular Tissue Engineering. Nanostructures for Musculoskeletal Tissue Engineering . SECTION V Regulatory Perspectives on Nanostructured Materials. Regulatory Process of Nanostructured Tissue Engineered Products. Index.