Description
Principles of Nucleic Acid Structure (2nd Ed.)
Authors: Neidle Stephen, Sanderson Mark
Language: EnglishSubjects for Principles of Nucleic Acid Structure:
Keywords
DNA; RNA; oligonucleotides; base pairing; backbone conformation; higher-order nucleic acids; major groove; minor groove; protein-DNA; protein-RNA interaction; A; B- and Z-DNA helices; Backbone conformations; Base and base pair morphology; Bending; Covalent binding; Dickerson-Drew dodecamer; DNA; DNA and RNA bases; DNA bending; DNA enzymes; DNA junctions; DNA mismatches; DNA recognition; DNA triple Helices; Fibre diffraction; Force fields; G-quartet; Groove binding; Helix and sheet; I-motif; Intercalation; Minor groove; Molecular dynamics; Molecular graphics; Nucleosomes; Proteins; Quadruplex DNA; Reverse transferases; Ribosomes; Riboswitches; Ribozymes; RNA helices; RNA structure; RNA-Protein complexes; Sequence dependency; Sequence recognition; Small nuclear ribonucleoproteins; Spine of hydration; Sugar puckers; Topoisomerases; tRNA synthetases; Unnatural DNA; Watson-Crick base pairs; X-ray crystallography; Z-DNA crystals
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Add to cart the book of Neidle Stephen, Sanderson Mark454 p. · 19x23.4 cm · Paperback
Description
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/li>Biography
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This reference is a must-have for those seeking an authoritative, comprehensive and up-to-date source on all aspects of nucleic acid structure, from basic first principles to details of recent research results.
2. The Building-Blocks of DNA and RNA
3. DNA Structure as Observed in Fibers and Crystals
4. Non-standard and Higher-Order DNA Structures: DNA–DNA Recognition
5. Principles of Small Molecule–DNA Recognition
6. RNA Structures and Their Diversity
7. Principles of Protein–DNA Recognition
8. RNA Binding Proteins
Mark Sanderson is a Visiting Professor of Biophysics in the Dept of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London. Recent structural studies in his laboratory have centred on type-II topoisomerase–DNA–drug complexes in collaboration with Prof. Mark Fisher’s group at St. George’s University of London using cryo-EM and X-ray crystallography, and the study of novel nucleic acid–protein complexes.
- Completely updated, with an expanded section on protein-nucleic acid interactions that reflects major increases in our knowledge
- Defines technical terms for novices
- Includes a complete list of resources, including relevant online databases and software, as well as useful websites