Description
Protein crystallography in drug discovery
Authors: BABINE Robert E., ABDEL-MEGUID Sherin S.
Language: EnglishSubjects for Protein crystallography in drug discovery:
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Add to cart the book of BABINE Robert E., ABDEL-MEGUID Sherin S.280 p. · 24x17 cm · Hardback
Description
/li>Contents
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A Personal Foreword.
List of Contributors.
1. Molecular Recognition of Nuclear Hormone Receptor Ligand Complexes (Robert E. Babine).
2. Kinases (Jerry L. Adams, James Veal, and Lisa Shewchuk).
3. The Proteasome as a Drug Target (Tsunehiro Mizushima and Tomitake Tsukihara).
4. Antibiotics and the Ribosome (Jeffrey L. Hansen).
5. Structure Based Design of Cathepsin K Inhibitors (Daniel F. Veber and Maxwell D. Cummings).
6. Structure Based Design of Potent and Selective Cdk4 Inhibitors (Teruki Honma).
7. Crystallization and Analysis of Serine Proteases with Ecotin (Sandra M. Waugh and Robert J. Fletterick).
8. X ray Crystallography in the Development of Orthogonal Ligand Receptor Pairs (Donald F. Doyle and Lauren J. Schwimmer).
9. Engineering Proteins to Promote Crystallization (Lei Jin and Robert E. Babine).
10. High throughput Crystallography (Harren Jhoti).
11. Micro Crystallization (Carl L. Hansen, Morten Sommer, Kyle Self, James M. Berger, and Stephen R. Quake).
Subject Index.