The Complex Interplay Between Gut-Brain, Gut-Liver, and Liver-Brain Axes

The Complex Interplay Between Gut?Brain, Gut?Liver, and Liver?Brain Axes provides current and wide-ranging information in the field of gastrointestinal, liver, and brain interactions that can be used in resolving important clinical issues. This book is systematically split into three distinct sections. The first section introduces the pathophysiology of the gut?brain connection, including the causative effect of the interactions between the gut and brain in gastrointestinal and psychiatric/neurological disorders, and the role of serotonin and its pathways in gastrointestinal disorders. The second section examines the pathophysiology of the gut?liver connection along with the interactions between gut microbiota and liver in chronic liver diseases, with special focus on the role of serotonin and its pathways in hepatic fibrogenesis. Finally, the third section describes the pathophysiology of the liver?brain connection, including the role of gut microbiota in hepatic encephalopathy, as well as dietary and therapeutic interventions that target the gut microbiome.

Section 1: Gut-brain axis
1. The Pathophysiology of gut-brain connection
2. The interactions between gut and brain in gastrointestinal disorders
3. The interactions between gut and brain in psychiatric/neurological disorders
4. The role of serotonin and its pathways in gastrointestinal disorders

Section 2: Gut-liver axis
5. The Pathophysiology of gut-liver connection
6. The role of gut microbiota in chronic liver diseases
7. The role of serotonin and its pathways in hepatic fibrogenesis

Section 3: Liver-brain axis
8. Gut
9. The gut-microbiota in hepatic encephalopathy
10. The Gut-Liver-Brain Axis: Dietary and therapeutic Interventions

In 2001, Cristina Stasi graduated with a degree in Medicine and Surgery at the Catholic University of the Sacred
Heart, Rome, Italy. In 2006, Dr. Stasi went on to specialize in Gastroenterology at the University of Pisa, Italy.
From 2006 to 2009, she took part in clinical research projects at the Careggi University Hospital in Florence,
Italy. At the same time, Dr. Stasi improved her knowledge in study design, management of clinical research
projects, statistics, and epidemiology. In 2013, she earned her PhD in Experimental and Clinical Medicine
from the University of Florence, Italy. Dr. Stasi has published more than 70 papers in reputed international
journals and serves as an editorial board member within international journals. She currently works at both the
MASVE Interdepartmental Hepatology Center (Department of Experimental and Clinical Medicine, University
of Florence and Center for Research and Innovation CRIA-MASVE, Careggi University Hospital, Florence,
Italy) as well as at the Epidemiology Unit (Regional Health Agency of Tuscany, Florence, Italy). Dr. Stasi has
obtained the National Scientific Qualification to work as an associate and full professor in the field of skin,
infectious, and gastrointestinal diseases in Italian universities and even to work as an associate professor in
the field of technology and methodology in medicine and nursing sciences, again in Italian universities.