Core-Shell Nanostructures for Drug Delivery and Theranostics
Challenges, Strategies and Prospects for Novel Carrier Systems
Woodhead Publishing Series in Biomaterials Series

Coordinators: Focarete Maria, Tampieri Anna

Language: English

258.68 €

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466 p. · 15x22.8 cm · Paperback

Core-Shell Nanostructures for Drug Delivery and Theranostics: Challenges, Strategies and Prospects for Novel Carrier Systems contains valuable chapters that deal with the fundamentals of nanotechnology for drug delivery, recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications, and the potential and applications of core-shell nanofiber. This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry.

Part I: Fundamentals on nanotechnology for drug delivery 1. Introduction to core-shell nanostructures for drug delivery 2. Physico-chemical properties of nanosized polymeric drug carrier systems 3. Biomineralization process generating hybrid nano-beads 4. Clinical applications of nanostructured drug delivery systems: from basic research to translational medicine

Part II: Core-shell nanoparticles 5. Core-shell nanoparticle technology 6. Core-shell nanoparticles for cancer therapy 7. Multifunctional hybrid Nanoparticles for Theranostics 8. Stimuli responsive core-shell nanoparticles 9. Magnetic core-shell nanoparticles: remote driving, hyperthermia and controlled drug release 10. Smart nano-systems for neurodegenerative diseases

Part III: Core-shell nanofiber 11. Coaxial electrospinning and emulsion electrospinning techniques 12. Drug release kinetics of electrospun fibrous systems 13. Applications of core-shell nanofibers: drug and biomolecules release and gene therapy 14. Core-shell nanofibers for multi-drug release

Researchers in biomaterials for drug delivery, materials science, polymer science, bioengineering, and biochemistry; graduate and postdoc students; R&D managers in the biomaterials and pharmaceutical industries.

Maria has authored more than 60 papers on international, peer-reviewed scientific journals and 3 book chapters.She is the inventor of 7 patents or patent applications. She has more than 100 contributions in national and international conferences in the fields of polymeric materials and electrospinning technology.
Maria coordinates the interdisciplinary Research Group on Electrospinning of the University of Bologna (RGE-UNIBO, that she founded in 2006) whose activities are mostly focused on extending basic current knowledge for better control and optimization of the electrospinning process and fabricating innovative engineered nanofiber assemblies from selected polymers. She also leads the Biomaterials Laboratory activities of the Health Sciences and Technologies - Interdepartmental Center for Industrial Research (HST-ICIR) at the University of Bologna. Technology transfer is also performed, and the electrospinning technology developed in the group are now the focus of a start-up company, where Maria is member of the Scientific Advisory Board.
Anna Tampieri, is the Director of the Institute of Science and Technology for Ceramics at the National Research Council of Italy, Chemist, 30 years of experience in Material Science, particularly addressed to biomimetic materials and devices for regeneration of hard and soft tissues and organs.
She authored more than 250 scientific papers published on peer-reviewed Journals and about 20 book chapters (H index = 38 based on Scholar).
She is inventor of 16 National and International patents, several of which are licensed to companies acting in the biomedical fields and translated to 7 commercial products.
She is Editor of a monography dealing with bio-inspired approaches in regenerative medicine, and Guest Editor of several international scientific journals.
Tutor of 11 Ph.D, 14 M.Sc students, and more than 20 National and International fellowships.
Coordinator of 5 EC-funded Projects belonging to the 6
  • Focuses on core-shell nanoparticles and nanofiber for innovative applications, including cancer therapy, controlled release and multi-drug release
  • Considers future prospects and potential new applications of core-shell nanostructures for drug delivery and theranostics
  • Explains the principles and essential concepts of nanotechnology for drug delivery systems