Polymeric Nanogels for Therapeutic and Diagnostic Applications
Woodhead Publishing Series in Biomaterials Series

Coordinators: Sadiku Emmanuel Rotimi, Sinha Ray Suprakas, Chijioke Adekoya Oluwasegun, Joseph Adekoya Gbolahan

Language: English

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470 p. · 15x22.8 cm · Paperback

Polymeric Nanogels for Therapeutic and Diagnostic Applications explores the design and use of polymer-based nanogels as multifunctional nanosystems for various biomedical applications. The book introduces the reader to the unique properties, characterization, synthesis, and functionalization of polymeric nanogels, providing a step-by-step overview of the core development aspects. A broad range of therapeutic and diagnostic applications is covered, from tissue regeneration, antimicrobial therapy, and cancer detection to treatment of neurological and metabolic disorders. This resource presents readers with a research-led and accessible reference to aid in the development of novel nanosystems.

1. Chemistry and Properties of Polymeric Nanogels 2. Molecular overview of diagnostic application of polymer nanogels 3. Ionotropic functionalization of polymer nanogels for delivery systems 4. Xenobiotic metabolism of synthetic biopolymers 5. Polymer nanogels for tissue repair and regeneration 6. Functionalized nanogels in diabetic treatment 7. Physiological and biochemical role of polymeric nanogels in oxidative stress 8. Polymeric nanogels for treatment of neurological disorders 9. Targeted gene modification using smart biopolymeric nanogels 10. Biohybrid nanogels for active target delivery 11. Polymeric nanogels for antimicrobial therapy 12. Self-assembled nanogels for treatment of respiratory infections 13. Polypeptide nanogels for metabolic disorder therapy 14. Enzymatic hybrid nanogel systems for degenerative diseases 15. Functionalized nanogels for cancer therapy 16. Conducting polymer-based nanogels for medical diagnostics

Prof. Rotimi Sadiku, currently a Professor at the Department of Chemical, Metallurgical, and Materials Engineering at Tshwane University of Technology, South Africa, earned his BSc. [Hons] and a PhD from the University of Strathclyde, Glasgow, UK, specializing in Polymer Physics with a focus on Polymer Processing, X-ray Diffraction, Thermal Characteristics, Rheology, and Microscopy of Polymers techniques.

His academic journey includes a role as a Lecturer II at the Federal University of Technology in Nigeria, followed by a Postdoctoral Research Fellowship at the University of Genova/CNR, Italy. Upon returning to Nigeria, he continued his career by joining the Federal University of Technology, where he served as a Senior Lecturer. He also spent a year as a Research Fellow at the KTH Institute of Technology in Stockholm, Sweden. In January 2004, he assumed his current position as a Research Professor at Tshwane University of Technology (TUT), South Africa.


Prof. Suprakas Sinha Ray is a Chief Researcher at the Council for Scientific and Industrial Research (CSIR), Pretoria, South Africa. He was awarded a Ph.D. in physical chemistry by the University of Calcutta in 2001 and is the Manager of the Center for Nanostructures and Advanced Materials and Director of the DSI-CSIR Nanotechnology Innovation Center. He is also affiliated with the University of Johannesburg as a Distinguished Visiting Professor of Applied Chemistry. Prof. Ray’s current research focus is on advanced nanostructured materials and their applications. His honours and awards include the 2013 Morand Lambla Awardee, International Polymer Processing Society; Distinguish Professor, King Abdulaziz University, Kingdom of Saudi Arab (2012); Extraordinary Professor, University of Pretoria, South Africa (2012); Global Star Award 2011 from the Engineering ceramic division, the American Ceramic Society; CSIR MSM Prestigious Established Researcher Award (2010); Prestigious CSIR President’s Award (2
  • Combines materials science, nanotechnology, and chemistry approaches to provide a multidisciplinary and comprehensive overview of polymeric nanogels in therapeutics and diagnostics
  • Details both the formulation and the application of polymeric nanogels, offering a holistic view
  • Covers a wide selection of therapeutic and diagnostic applications, such as targeted gene modification, targeted substrate delivery, biosensing, treatment of degenerative diseases, and more