Description
Antimicrobial Peptides
Challenges and Future Perspectives
Coordinators: Ajesh K., Sreejith K.
Language: English
Subjects for Antimicrobial Peptides:
Keywords
AMP; AMPs; Alpha-defensins; Amino acid analysis; Amphibian peptides; Amphipathic; Antibiotic resistance; Antibiotics; Antibody; Antimicrobial activity; Antimicrobial peptide; Antimicrobial peptides; Antimicrobial peptides (AMPs); Antiviral drug; Antiviral peptides; Anuran peptides; Bacillus; Bacteriocins; Bioactivity; Cathelicidin; Cathelicidins; Cationic; Cationic peptides; Cecropins; Chromatography; Clinical developments; Computational biology; Defensins; Drug design; ESKAPE pathogens; a-aminoisobutyric acid; ß-defensins; Epimerization; Gram-negative bacteria; Gram-positive bacteria; HPLC; Histatin; History; Host defense peptides; Innate immune peptides; Innate immunity; Insect peptides; Insects; Interactions; Lipopeptides; Lysozyme; MALDI-TOF-MS; MS/MS; Machine learning; Macrocyclization; Magainin; Mammalian antimicrobial peptides; Marine environment; Mass spectrometry; Membrane; Modification; Modified peptides; Multidrug resistance (MDR); NRPSs; Nanoconjugated peptide; Peptaibols; Peptide drug; Peptide engineering; Perturbation; Petaibiotics; Phagocytic cells; Pharmaceutical market; Plant-derived peptides; Protein; Pseudomonas; RiPPs; Sequencing; Small peptides; Specificity; Surfactants; Therapeutics; Thrombocidine; Timeline; Trichoderma; Vancomycin; Viral inhibitor; Western Ghats
346 p. · 15.2x22.8 cm · Paperback
Description
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Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides.
Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development.
2. Biosynthesis of peptide antibiotics and innate immunity
3. Antimicrobial peptides: features and mode of action
4. Purification techniques and characterisation of antimicrobial peptides
5. Peptide antibiotics from bacteria
6. Antimicrobial peptides of fungal origin
7. Insect peptides with antimicrobial effect
8. Amphibian host defence peptides
9. Plant derived antimicrobial peptides
10. Mammalian antimicrobial peptides
11. Antimicrobial peptides from marine environment
12. Peptides with antiviral activities
13. Peptide antibiotics against MDR bacteria
14. Antimicrobial peptide resistance
15. Recent advances and challenges in peptide drug development
16. Future perspective of peptide antibiotic market
He is also the Research Director of Kannur University since 2018. Dr. Sreejith has received MPhil in Biophysics and PhD in Biochemistry from Mahatma Gandhi University, Kerala, India. He has more than 19 years of teaching and research experience. His area of research is antimicrobial peptides and proteins, anti inflammatory compounds and cancer biology. Since 2008, his team has contributed extensively in the aforementioned area with publications appearing in the Journal of Applied Microbiology, Applied Biochemistry and Biotechnology, Peptides, Mycopathologia. He has presented papers in the II International conference on antimicrobial research, Lisbon, Portugal-2012 and European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), Amsterdam (Netherlands) in 2016. He is a life member of Indian Peptide Society (IPS). Since 2003 he has been serving Kannur University in its Board of studies in Microbiology as a member and from 2010 onwards he is the Chairman. He is having collaboration with researchers, Dr Sudarslal, Professor, School of Biotechnology, Amrita Vishwa
- Emphasizes antimicrobial peptides targeting various human viruses and multidrug resistant bacteria
- Written by internationally recognized experts who provide readers with a wide and useful perspective
- Provides in-depth resources for undertaking a research work in antimicrobial peptides with the inclusion of chapters on purification techniques and structural details
- Addresses the possibility and availability of peptide antibiotics in the global drug market
- Serves as a complete resource from the discovery to drug development of peptide antibiotics
