Description
Brain Tumors, 1st ed. 2021
Neuromethods Series, Vol. 158
Coordinator: Seano Giorgio
Language: EnglishSubjects for Brain Tumors:
Brain Tumors
Publication date: 09-2021
370 p. · 17.8x25.4 cm · Paperback
Publication date: 09-2021
370 p. · 17.8x25.4 cm · Paperback
Brain Tumors
Publication date: 09-2020
Support: Print on demand
Publication date: 09-2020
Support: Print on demand
Description
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This volume explores the latest models and techniques used to study brain tumor biology. Chapters in this book are organized into four sections: in vivo models, ex vivo models, treatments in mice, and clinical imaging. Some of the topics covered in this book are in vivo preclinical models of lower-grade gliomas, medulloblastoma, and brain metastases; ex vivo methods for glioblastoma patient-derived cell lines and organotypic brain cultures for metastasis; in vivo treatments of preclinical models that assess neurological function, dynamic immunotherapy, and neurological impacts of brain irradiation; and clinical imaging and modeling, such as biomechanics and vascular perfusion. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Cutting-edge and practical, Brain Tumors is a valuable resource that will help readers understand the heterogeneity of the techniques used to study the complexity of brain tumors.
Series Preface…
Acknowledgements…
Preface…
Table of Contents…
Contributing Authors…
Part I In Vivo Models
Sofia Archontidi, Sandra Joppé, Yanis Khenniche, Chiara Bardella, and Emmanuelle Huillard
2. In Vivo Medulloblastoma Modeling
Liliana Mirabal-Ortega, Magalie Larcher, Morgane Morabito, Chloé Foray, Bertrand Duvillié, Alain Eychène, and Celio Pouponnot
3. In Vivo Models of Brain Metastases
Christina S. Wong
4. Intravital Imaging of Brain Tumors
Cathy Pichol-Thievend, Boris Julien, Océane Anézo, Beatrice Philip, and Giorgio Seano
Part II Ex Vivo Models
5. Glioblastoma Patient-Derived Cell Lines: Generation of Non-Adherent Cellular Models from Brain Tumors
Joris Guyon, Tiffanie Chouleur, Andreas Bikfalvi, and Thomas Daubon
6. Organotypic Brain Cultures for Metastasis Research
Lucía Zhu and Manuel Valiente
7. Human Glioblastoma Organoids to Model Brain Tumor Heterogeneity Ex Vivo
W. Dean Pontius, Lisa C. Wallace, Katrina Fife, and Christopher G. Hubert
8. In Vitro Mechanobiology of Glioma: Mimicking the Brain Blood Vessels and White Matter Tracks Invasion Paths
Pascale Monzo, Michele Crestani, and Nils C. GauthierPart III Treatments in Mice
9. Assessing Neurological Function in Brain Tumor Mouse Model
Xing Gao, Limeng Wu, Raquel D. Thalheimer, Jie Chen, Yao Sun, Grace Y. Lee, Scott R. Plotkin, and Lei Xu
10. Dynamic Immunotherapy Study in Brain Tumor-Bearing Mice
Luiz Henrique Medeiros Geraldo, Yunling Xu, and Thomas Mathivet
11. Experimental and Preclinical Tools to Explore the Main Neurological Impacts of Brain Irradiation: Current Insights and Perspectives
Laura Mouton, Monica Ribeiro, Fawzi Boumezbeur, Denis Le Bihan, Marc-André Mouthon, Damien Ricard, François Boussin, and Pierre Verrelle
Part IV Clinical Imaging
12. Mechano-Biological Features in the Patient-Specific Computational Model of Glioblastoma
Francesco Acerbi, Abramo Agosti, Jacopo Falco, Stefano Marchesi, Ignazio G. Vetrano, Francesco DiMeco, Alberto Bizzi, Paolo Ferroli, Giorgio Scita, and Pasquale Ciarletta
13. Magnetic Resonance Imaging for Quantification of Brain Vascular Perfusion
Line Brennhaug Nilsen and Kyrre Eeg Emblem
14. MRI Morphometry in Brain Tumors: Challenges and Opportunities in Expert, Radiomic, and Deep-Learning Based Analyses
Marco C. Pinho, Pallavi Tiwari, Kaustav Bera, and Niha Beig
Subject Index List...
Includes cutting-edge methods and protocols
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts
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