Carbohydrate Chemistry
Proven Synthetic Methods, Volume 3
Carbohydrate Chemistry: Proven Synthetic Methods Series

Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of characterization data for new compounds, and inflated yields reported in chemical communications?trends that have recently become a serious problem.

Featuring contributions from world-renowned experts and overseen by a highly respected series editor, Carbohydrate Chemistry: Proven Synthetic Methods, Volume 3 compiles reliable protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences.

Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. To ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods.

The book includes new or more detailed versions of previously published protocols as well as those published in not readily available journals. The essential characteristics of the protocols presented are reliability and the expectation of wide utility in the carbohydrate field. The protocols presented will be of wide use to a wide range of readers in the carbohydrate field, including undergraduates taking carbohydrate workshops.

Synthetic Methods. Synthetic Intermediates.

Rene Roy was born in Québec, Canada. He holds a Canadian Research Chair in therapeutic chemistry in the Department of Chemistry at the Université du Québec à Montréal, Québec, Canada since 2004. He has more than 40 years of experience in carbohydrate chemistry. He earned his PhD in carbohydrate chemistry in 1980 from the Université de Montréal, under the expert guidance of Professor Stephen Hanessian. He joined the National Research Council of Canada in Ottawa (Canada), where he was active from 1980 till 1985, and acquainted himself with carbohydrate-based vaccines. He then served as a professor at the Department of Chemistry, University of Ottawa, during 1985–2002. He was the recipient of the 2003 Melville L. Wolfrom Award from the ACS Division of Carbohydrate Chemistry for his contributions in the design of vaccines and glycodendrimers. He has more than 310 publications and has contributed to the development of two commercial carbohydrate-based vaccines against meningitis. His current interests are in multivalent carbohydrate protein interactions, medicinal chemistry, and nanomaterials.

Sebastien Vidal is a Centre National de la Recherche Scientifique (CNRS) researcher at the University of Lyon, Lyon, France. He earned his PhD in organic chemistry (2000) at the University of Montpellier, France, under the guidance of Professor Jean-Louis Montero, where he synthesized mannose-6-phosphate analogues for drug delivery applications. He then joined the group of Sir J. Fraser Stoddart at the University of California, Los Angeles (UCLA) as a postdoctoral fellow. During the following two and a half years, he studied the synthesis and characterization of glycodendrimers but also the design of pseudorotaxanes. In 2003, he moved to the National Renewable Energy Laboratory (NREL, Golden, Colorado) and studied with Prof. Joseph J. Bozell the combination of organometallic and carbohydrate chemistries for the design of new reactions in