Diabetes Mellitus
Impact on Bone, Dental and Musculoskeletal Health
Bones, Joints, and Hormones Series

Coordinator: Tan Meng Hee

Language: English
Cover of the book Diabetes Mellitus

Subject for Diabetes Mellitus

Keywords

Adhesive capsulitis; Amputation; Aspirin; Bisphosphonates; Bone; Bone biopsy; Bone complications; Bone density; Bone turnover; Carpal tunnel syndrome; Cartilage; Charcot foot; Chronic kidney disease; Clinical presentation; Denosumab; Dental; Dental implants; Diabetes; Diabetes complications; Diabetes mellitus; Diabetic amyotrophy; Diabetic bone disease; Diabetic foot; Diabetic lumbosacral radiculoplexus neuropathy; Diabetic radiculoplexus neuropathy; Diagnosis; Dialysis; Diffuse idiopathic skeletal hyperostosis; Dupuytren disease; Epidemiology; Falls; Fibroblast growth factor-23; Fracture; Fracture risk; Fractures; Fructose; Genetics; Glucose-lowering medications; Gout; Health; Hemoglobin A1C; Hyperglycemia; Hyperparathyroidism; Hyperuricemia; Immunosuppression; Infection; Inflammasome; Limited joint mobility; Macrovascular; Metabolic dysfunction; Metabolic syndrome; Microvascular; MRONJ; Musculoskeletal complications; Myonecrosis; Neuroarthropathy; Neuropathy; Obesity; Ossification of the posterior longitudinal ligament; Osteoarthritis; Osteomyelitis; Osteonecrosis; Osteoporosis; Osteoporotic fracture; Oxidative stress; Pathogenesis; Pathophysiology; Peri-implantitis; Periodontal disease; Periodontitis; Risk factor; Rotator cuff tendinopathy; Skeletal fragility; Skeletal muscle; Synovium; Trabecular bone score; Treatment of sarcopenia and diabetes mellitus; Trigger digit; Trigger finger; Type 1 diabetes; Type 2 diabetes; Type 2 ­diabetes; Ulcer; Urate transporter; Vasculature; Wound healing

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Diabetes Mellitus: Impact on Bone, Dental and Musculoskeletal Health focuses on the under recognized and managed conditions associated with diabetes, including impacts on bone health, dental health, hand, and foot disorders, wounds, infections, and musculoskeletal disorders. A full understanding of the relationship of diabetes to skeletal disorders remains elusive and many physicians who deal with such issues are unclear about causes and management. While the macro- and microvascular complications associated with diabetes mellitus are well known, complications associated with bone, dental and musculoskeletal health are not.

Endocrinologists, primary care physicians, geriatricians, podiatrists, dentists, and researchers interested in diabetes mellitus associated bone, dental and musculoskeletal disorders will find this to be a comprehensive tome on the topic.

1. Diabetes mellitus and its many complications

Section I: Impact on bone health 2. Diabetes mellitus: How being too sweet leads to skeletal fragility 3. Mechanisms of skeletal fragility in diabetes mellitus 4. Impact of glucose-lowering medications on bone health in diabetes 5. The combined impact of diabetes mellitus and chronic kidney disease on mineral metabolism and bone fragility 6. Diabetes mellitus—Infections and fracture healing

Section II: Impact on dental health 7. Diabetes mellitus—Dental implants and periodontal disease 8. Diabetes mellitus and its association with infection and osteonecrosis of the jaw

Section III: Impact on musculoskeletal health 9. Diabetes mellitus and sarcopenia 10. Diabetes mellitus: Impact on common hand disorders 11. Musculoskeletal disorders associated with diabetes 12. Neuropathic arthropathy (Charcot joint) 13. Diabetes mellitus and muscle infarction 14. Diabetes mellitus and osteoarthritis 15. Diabetes mellitus and gout

The target audience includes researchers (academic and industry), academic and practicing clinicians (endocrinologists, primary care physicians, geriatricians, podiatrists, physiatrists, dentists, surgeons, etc), undergraduate and graduate medical students, and other healthcare providers (nurse-practitioners, physician assistants, diabetes educators, pharmacists, etc).

MengHee Tan, MD, FACP, FRCP [C], [L], [E], FACE, is Professor Emeritus of Internal Medicine, Division of Metabolism, Endocrinology & Diabetes, University of Michigan. Earlier in academia at Dalhousie University, Halifax, Canada, he was Professor of Medicine and Biochemistry and Head, Division of Endocrinology & Metabolism. He was also Head, Department of Medicine, Halifax Infirmary and Camp Hill Medical Center. After leaving Dalhousie, he became Medical Director of Diabetes Disease Management at Becton Dickinson and Company. Later, he was a Distinguished Medical Fellow at Lilly Research Laboratories and Senior Global Medical Director, Diabetes Endocrine Platform Team at Eli Lilly and Company. His research interests span from unravelling the biology of skeletal muscle to uncovering new knowledge on pharmacotherapy for people with diabetes and dyslipidemias. He has published over 200 research/clinical papers and chapters on diabetes, lipoprotein metabolism, and endocrinology. He was the inaugural Editor-in-Chief of Clinical Diabetes and Endocrinology.
He is past President of the Canadian Diabetes Association, Chair of the Canadian Diabetes Advisory Board, and Vice-President of the International Diabetes Federation. He received the Harold Rifkin Award from the American Diabetes Association and the Charles H Best Award from the Canadian Diabetes Association.
  • Covers clinically important complications of diabetes that are less understood
  • Presents up-to-date, thoroughly referenced information for both clinicians, researchers and other healthcare providers
  • Highlights current research and treatment for skeletal deficits and complications due to diabetes types 1 and 2
  • Serves as a one-stop resource for the bone, dental and muscular disorders associated with diabetes mellitus