FOGSI Focus: Use of Adjuvants in Infertility

Fertility specialists are constantly looking for ways to improve the chances of pregnancy through IVF or other assisted reproductive techniques (ART). ?Adjuvant? or ?add-on? therapies are procedures or medications which are added to IVF treatment to try and improve the chances of success.  

This book is a practical guide to the use of adjuvants in infertility for clinicians and trainees.

Divided into ten sections, the text begins with an overview of the rational for additional therapy in IVF. The next section examines different types of adjuvant therapy and their pros and cons. Topics include medical nutrition therapy, neutraceuticals, antioxidants, micronutrients, and reactive oxygen species.

Each of the following sections covers adjuvant use for improving a specific fertility issue ? PCOS, ovarian reserve, uterine blood flow, endometrial receptivity, embryo implantation, and male subfertility.

The final sections discuss the impact of thyroid autoimmunity on the outcome of ART, and the use of surgery as an adjuvant in infertility.

Key points

• Practical guide to the use of adjuvants in infertility
• Covers various types of adjuvant and their use for different fertility issues
• Includes discussion on surgery as an adjuvant
• Highly illustrated with clinical photographs and diagrams

1. Rational for additional therapy in IVF
2. Various options of additional therapy in IVF with best available evidence for each suggested therapy - An overview
3. Current controversies & consensus for adjuvants in PCOS
4. Adjuvants for improving ovarian reserve in poor responders
5. Adjuvants for improving uterine blood flow
6. Adjuvants for improving endometrial receptivity/luteal phase
7. Adjuvants for improving the implantation potential of the embryo
8. Adjuvants in male sub-fertility
9. Impact of thyroid autoimmunity on outcomes of assisted reproduction
10. Surgery as adjuvant in infertility

Nandita Palshetkar MD FCPS FICOG FRCOG
President FOGSI 2019; Scientific Director, Bloom IVF; Professor, Department of Obstetrics and Gynaecology, Dr DY Patil Medical College Hospital and Research Centre, Navi Mumbai, Maharashtra, India