Fundamental Principles of Oxidative Stress in Metabolism and Reproduction
Prevention and Management

Coordinators: Alam Faiza, Rehman Rehana

Language: English
Cover of the book Fundamental Principles of Oxidative Stress in Metabolism and Reproduction

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260 p. · 19x23.3 cm · Paperback

Fundamental Principles of Oxidative Stress in Metabolism and Reproduction: Prevention and Management is a comprehensive resource for anyone needing awareness and recognition of oxidative stress as a basic component of disease to determine the precise treatment plan considering the cause of the disease. It describes the effects of oxidative stress in the human body, the detection of metabolic changes, psychological impact and effect on reproductive outcomes. In addition, it discusses alterations at the cellular level occurring due to oxidative stress along with the genetic aspects involved in its pathogenesis.

SECTION I: Overview: Cause and Mechanisms 1. Introduction to Oxidative Stress 2. Role of free radicals in normal human physiology 3. Role of Diet In development of Oxidative stress 4. Occupational hazards and Oxidative stress 5. Role of environmental in development of Oxidative stress 6. Role of radio-frequency electromagnetic waves in causing oxidative stress 7. Genetic Variations and Lifestyle in Oxidative Stress 8. Effect of Ageing on Generation of Oxidative stress Section II: Systemic Effects of Oxidative Stress 9. Oxidative Stress and Insulin Resistance 10. Oxidative stress and Cardiovascular Diseases 11. Oxidative stress and Chronic kidney Disease 12. Oxidative stress in neurodegenerative disorders 13. Oxidative stress, mechanisms and Subfertility in Female 14. Oxidative stress, mechanisms and Subfertility in Male 15. Oxidative stress, varicocele and disorders of male reproduction 16. Oxidative stress, Vitamin D deficiency and Subfertility 17. Oxidative role on oncogenesis 18. Oxidative stress in Cancer Cell death SECTION III: Management 19. Overview of prevention and management of OS 20. Current antioxidant medicinal regime and treatments used to alleviate oxidative stress in infertility issues 21. Role of Complementary and Alternative Medicine in Management of Oxidative Stress

Dr Faiza Alam is an Assistant Professor at Pengiran-Anak-Puteri-Rashidah-Sa’adatul-Bolkiah Institute of Health Sciences, Brunei Darussalam, and previously worked at Aga Khan University from 2014-2017. She has been teaching Physiology for the last 14 years. Broadly, her research is aimed towards the causative factors of non-communicable diseases, including obesity, diabetes and their effects on fertility. Dr Alam educates students to follow ethical principles of research, manuscript, synopsis and thesis writing. She has conducted workshops on the “Flipped Classroom Teaching style” in Pakistan and Brunei. She has published in international journals and is an editor of the research topics in Frontiers journals; “Vitamin D Deficiency and Sufficiency in Reproduction and Bone Metabolism” and “Recent Advances in Vitamin D Supplementation for Improved Reproductive Endocrine and Metabolic Parameters”.


Dr. Rehana Rehman has an experience of teaching Physiology for more than 2 decades. She is a well-recognized authority in the field of Reproductive Physiology working to identify treatable causes of childlessness in collaboration with infertility centers in Pakistan. Her research contributes towards fetal, infant as well as maternal wellbeing; an effort to attain the “Sustainable Development Goals”. She has more than 200 manuscripts and 6 books published as an author with a citation index of 3116 and h-index of 29. She is supervising M.Phil. and PhD students in a number of allied universities. Organizing and conducting workshops, competence based trainings and courses are proof of delivering competencies to others and reflect a sign of continued growth and productivity on her behalf.
  • Provides a holistic approach to the impact of oxidative stress on various systems
  • Incorporates recent advances in basic sciences for improvement in oxidative stress leading to better prognosis of metabolic conditions
  • Summarizes knowledge to detect oxidative stress for improvement of fertility outcomes