Description
GABA and Sleep, 2010
Molecular, Functional and Clinical Aspects
Coordinators: Monti Jaime M., Pandi-Perumal Seithikurippu Ratnas, Möhler Hanns
Language: EnglishSubject for GABA and Sleep:
Keywords
Publication date: 09-2014
486 p. · 15.5x23.5 cm · Paperback
Publication date: 09-2010
486 p. · 15.5x23.5 cm · Hardback
Description
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GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. The GABA system is, therefore, of prime clinical relevance for the therapy of insomnia.
The focus of this volume is on the neuropsychopharmacology and the clinical impact of the GABA system in regulating sleep and wakefulness. It presents molecular, neuropharmacological, systems-biological and clinical approaches to the understanding of the mechanism of action of GABA and GABAergic drugs. It also explores the role of GABA in the basic drives that affect sleep, and the influences that adapt sleep and wakefulness to external events.
Focuses on the neuropsychopharmacology of GABA and its role in sleep and wakefulness
Presents neurochemical, electrophysiological, and neuropharmacological approaches to understand GABAergic mechanisms
Offers an overview of current approaches and medications
Features contributing authors who are leading experts in the field of sleep and neuropharmacology
Includes supplementary material: sn.pub/extras