Immuno-Oncology Progress in Tumor Research Series, Vol. 42

Over the last decade, immuno-oncology has witnessed an astonishing pace of discovery and innovation, translating into unprecedented successes in the clinical setting, arguably representing one of the most profound and transforming revolutions in the history of cancer therapy.

This book provides a concise and accurate outline of the main developments in major tumor types including melanoma, lung, breast, brain and renal cell cancers. In addition, chapters that describe the commonalities of

some of the therapeutic strategies are provided to cover topics like immune checkpoint biology, T cell engineering or rational combination therapies. Each chapter is authored by senior key opinion leaders in their respective fields to provide the most up-to-date view on cancer immuno-oncology. To reflect on the key translational aspect of immuno-oncology,all chapters are making explicit connections between basic science discoveries and the resulting translational therapeutic strategies.

Immuno-Oncology will be an invaluable source of information for scientists interested in the translation of basic immunology into the clinical practice, as well as for clinicians interested in deepening their knowledge of current

and upcoming immune strategies in the fight against cancer.

- Preface
- Immunotherapies in Early and Advanced Renal Cell Cancer
- Immunotherapy of Brain Tumors
- Immunotherapy of Melanoma
- Immunotherapy of Breast Cancer
- Current Developments in Actively Personalized Cancer Vaccination with a Focus on RNA as the Drug - Format
- Immune Checkpoint Inhibitors
- Radiotherapy and Immunotherapy: Improving Cancer Treatment through Synergy
- Combinations Therapies
- Promise of Immunotherapy in Lung Cancer
- T Cell Engineering
- Author
- Index