Macrophages Biology and Tissue Inflammation in Health and Disease

Macrophages Biology and Tissue Inflammation in Health and Disease outlines the important role of macrophages?keys cells in the innate immune system?as regulators and orchestrators of inflammation and repair in health and disease. It contains chapters by leading authors on the basic and translational aspects of macrophage biology, covering how to maintained tissue homeostatis and how to deal with internal and external biological threats.

I. Macrophages and Inflammation
1. Development of the monocyte-macrophage lineage
2. Types of macrophages
3. Acute and chronic inflammation: The basics

II. Biology
4. Macrophage biology in inflammation: cytokines
5. Macrophage biology in inflammation: chemokines
6. Macrophage biology: other factors
7. The importance of crosstalk between macrophages and other cell types
8. Macrophages in tissue engineering and regeneration

III. Role of Macrophages in systemic inflammation
9. CVS
10. Pulmonary
11. GI
12. CNS
13. Musculoskeletal system
14. Cancer

IV. Conclusions
13. Role of Macrophages in mediating Homeostatic Processes
14. Up and coming research fields

Professor with Tenure in the Department of Orthopaedic Surgery at Stanford University with a courtesy appointment in the Department of Bioengineering at Stanford University. Dr. Goodman received his BSc, MD and MSc (Institute of Medical Science) from the University of Toronto, and his PhD in Orthopedic Medical Science from Lund University in Sweden. His clinical research interests center on the outcome of surgery for arthritis including primary and revision total joint replacement, juvenile arthritis, and osteonecrosis of the hip and knee. His basic science interests center on biocompatibility of orthopaedic implants, inflammation, and musculoskeletal tissue regeneration and repair. Dr. Goodman is on the editorial board of the Journal of Orthopaedic Research (Associate Editor), Clinical Orthopaedics (Deputy Editor-Hip Society Liason), Biomaterials (Associate Editor), Journal of Arthroplasty, Journal of Biomedical Materials Research, and other journals, and is a manuscript reviewer for over 20 journals in the fields of orthopaedic surgery, arthritis, bioengineering and biomaterials. Dr. Goodman has published over 500 peer-reviewed manuscripts in medical and bioengineering journals.
Dr. Takagi received his BSc, MD, and PhD from the Yamagata University. His research carrier started in 1986, focused on cellular function of macrophages in relation to bone resorption and foreign body reaction, as well as rheumatoid arthritis and allied diseases. As a visiting researcher of Ph.D. program at the University of Helsinki, supervised by late Professor Seppo Santavirta and late Professor Yrjö Konttinen. learned importance of translational research, bench-to-bedside, and research mind. Has experience with joint reconstructive surgeries for 30 years, carrier of basic research and supervising Ph.D. students and leadership of teams consisting of surgeons, clinicians, pathologists, molecular biologists, bioengineers, biostatisticians and other related professionals for the transl