Neoplastic Diseases of the Blood (6th Ed., 6th ed. 2018)

Coordinators: Wiernik Peter H., Dutcher Janice P., Gertz Morie A.

Language: English

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Neoplastic Diseases of the Blood
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Neoplastic Diseases of the Blood
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The new edition of this textbook integrates the history, epidemiology, pathology, pathophysiology, therapeutics, and supportive care of modern neoplastic hematopathology. Now in its sixth edition, this classic and invaluable text brings together a team of internationally renowned experts and offers in-depth coverage of the complex interface between diagnosis and therapy. The textbook is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia, including chronic leukemias and related disorders, acute leukemias, myeloma and related disorders, and lymphomas, and the fifth section covering a variety of topics in supportive care. Chapters are presented in an accessible and easy-to-read layout, providing updates on the tremendous progress made in the last decade in the understanding of the nature of hematologic malignancies and their treatment.

Neoplastic Diseases of the Blood, Sixth Edition is an authoritative and indispensable resource for students, trainees, and clinicians, sure to distinguish itself as the definitive reference on this subject.
Part I Chronic Leukemias and Related Disorders

Ch 1: A History of the Chronic Leukemias
George P. Canellos, Matthew S. Davids

Ch 2: Epidemiology and Etiology of Chronic Myeloid Leukemia
Maren Rohrbacher, Joerg Hasford

Ch 3: Pathology of the Chronic Myeloid Leukemias
Barbara J. Bain

Ch 4: Molecular Biology and Cytogenetics of Chronic Myeloid Leukemia
Marina Konopleva, Alfonso Quintas Cardama, Hagop Kantarjian, Jorge Cortes

Ch 5: Diagnosis and Treatment of Chronic Myeloid Leukemia
Charles A. Schiffer

Ch 6: Etiology and Epidemiology of CLL
Helen E. Speedy, Daniel Catovsky, Richard S. Houlston

Ch 7: Morphology and Immunophenotype of CLL
Mir Basharath Alikhan, Grish Venkataraman

Ch 8: The Genomic and Epigenomic Landscape of Chronic Lymphocytic Leukemia
Jonathan C. Strefford, Renata Walewska, David G. Oscier

Ch 9: Treatment of Chronic Lymphocytic Leukemia and Related Disorders
Deepa Jeyakumar, Susan O’Brien

Ch 10: Hairy Cell Leukemia
Sonia Ali, Alan Saven

Part II Acute Leukemias

Ch 11: History of Acute Leukemia
Emil J. Freireich

Ch 12: The Etiology of Acute Leukemia
Jessica N. Nichol, Mena Kinal, Wilson H. Miller, Jr.

Ch 13: Epidemiology and Hereditary Aspects of Acute Leukemia
Logan G. Spector, Erin L. Marcotte, Rebecca Kehm, Jenny N. Poynter

Ch 14: Classification of the Acute Leukemias: Cytochemical and Morphologic Considerations
N. Nukhet Tuzuner, John M. Bennett

Ch 15: Immunobiology of Acute Leukemia
Elisabeth Paietta

Ch 16: Cytogenetics of Acute Leukemia
Nyla A. Heerema, Susana Catalina Raimondi

Ch 17: Diagnosis and Treatment of Childhood Acute Lymphoblastic  
Leukemia 
Lewis B. Silverman, Melinda Pauly

Ch 18: Diagnosis and Treatment of Adult Acute Lymphocytic Leukemia
Nicola Goekbuget, Dieter Hoelzer

Ch 19: Diagnosis and Treatment of Acute Myeloid Leukemia in Children
Brenton G. Mar, Barbara Degar

Ch 20: Diagnosis and Treatment of Adult Acute Myeloid Leukemia Other than Acute Promyelocytic Leukemia
Peter H. Wiernik

Ch 21: Acute Promyelocytic Leukemia
Peter H. Wiernik, Robert E. Gallagher, Martin S. Tallman

Ch 22: Therapy-Related Acute Myelogenous Leukemia
Hyun Chan Suh, H. Phillip Koeffler

Ch 23: The Myelodysplastic Syndromes
Kenneth Miller, Monika Pilichowska

Part III Myeloma and Related Diseases

Ch 24: History of Multiple Myeloma
David P. Steensma, Robert A. Kyle

Ch 25: Monoclonal Gammopathy of Undetermined Significance
Malin Hultcrantz, Ola Landgren

Ch 26: Smoldering Multiple Myeloma
Maria Victoria Mateos, Jesus San-Miguel

Ch 27: Newly Diagnosed Multiple Myeloma in Frail Patients
Alessandra Larocca, Antonio Palumbo

Ch 28: Newly Diagnosed Multiple Myeloma in Transplant Eligible Patients 
Rajshekhar Chakraborty, Morie A. Gertz

Ch 29: Role of Hematopoietic Cell Transplantation for Myeloma
Heather Landau, Sergio Giralt

Ch 30: Solitary Plasmacytomas and Soft-Tissue Involvement in Multiple Myeloma
Joan Bladé, Laura Rosiñol

Ch 31: Supportive Care in Multiple Myeloma
Simit Mahesh Doshi, Tom T. Noff, G. David Roodman

Ch 32: POEMS Syndrome
Angela Dispenzieri  

Ch 33: Waldenstrom's Macroglobulinemia
Steven P. Treon, Giampaolo Merlini, Meletios Dimopoulos

Ch 34: Plasma Cell Leukemia
Nisha S. Joseph, Sagar Lonial

Ch 35: Prognosis of Myeloma/Genetics of Myeloma
Sébastien Robiou-Du-Pont, Jill Corre, Hervé Avet-Loiseau

Ch 36: Immunoglobulin Light Chain Amyloidosis (AL)
Morie A. Gertz, Francis K. Buadi, Taimur Sher, Angela Dispenzieri

Part IV Lymphoma

Ch 37: Historical Landmarks in an Understanding of the Lymphomas
Marshall A. Lichtman

Ch 38: Genetics in Lymphomagenesis
James R. Cerhan, Esteban Braggio, Susan L. Slager, Anne J. Novak

Ch 39: Epidemiology and Hereditary Aspects of Hodgkin and Non-Hodgkin Lymphomas
Seymour Grufferman

Ch 40: Pathology of Non-Hodgkin and Hodgkin Lymphomas
Mariko Yabe, L. Jeffrey Medeiros

Ch 41: Immunology of the Lymphomas
Christopher Sequeira, Howard Ozer

Ch 42: Cytogenetics of Lymphomas
Meaghan Wall, Lynda J. Campbell

Ch 43: Diagnosis and Treatment of Hodgkin Lymphoma
Peter H. Wiernik

Ch 44: Radiotherapeutic Management of Lymphomas
John P. Plastaras, Eli Glatstein

Ch 45: Diagnosis and Treatment of Non-Hodgkin’s Lymphoma of Adults
David G. Crockett, James O. Armitage, Julie M. Vose

Ch 46: Non-Hodgkin Lymphoma of Childhood
Tony H. Truong, Sarah Alexander, Sheila Weitzman

Ch 47: Lymphoma in Other Diseases
Jennifer Crombie, Dan L. Longo

Part V Supportive Care

Ch 48: Supportive Care for Patients with Leukemia: A Historical Perspective
Charles A. Schiffer

Ch 49: Prevention of Infections in Patients with Hematological Malignancies
Marcio Nucci, Elias J. Anaissie

Ch 50: Evaluation and Management of Bacterial and Fungal Infections in Patients with a Hematological Malignancy: A 2016 Update
Maria Pia Franco, Jaime S. Green, Jo-Anne H. Young

Ch 51: Viral Infections in Patients with Hematological Malignancies
Jack W. Hsu, John W. Hiemenz, John R. Wingard, Helen Leather

Ch 52: Therapeutic Cytapheresis, Plasmapheresis, and Plasma Exchange in Neoplastic Diseases of the Blood
Janice P. Dutcher

Ch 53: Red Cell Transfusions in Patients with Hematologic Malignancies
Karen E. King, Paul M. Ness

Ch 54: Platelet and Granulocyte Transition
Janice P. Dutcher

Ch 55: Alternative Sources of Hematopoietic Stem Cells and Their Clinical Applications
Filippo Milano, Shelly Heimfeld, H. Joachim Deeg

Ch 56: HLA Typing in Support of Hematopoietic Cell Transplantation from Unrelated Donors
Effie W. Petersdorf, Claudio Anasetti, Paul J. Martin, John A. Hansen

Ch 57: Special Care of Blood and Marrow Hematopoietic Cell Transplant Recipient
Syed Abutalib, Hillard M. Lazarus

Ch 58: Hematopoietic Growth Factors in the Supportive Care and Treatment of Patients with Hematologic Neoplasms
Ryan W. Jacobs, Omotayo Fasan, Edward A. Copelan, Belinda R. Avalos

Ch 59: Bleeding and Thrombosis in Hematologic Neoplasia
Joseph J. Shatzel, Robyn Scherber, Thomas G. DeLoughery

Ch 60: Psychological Aspects of Hematological Neoplasms
Tomer T. Levin, Judith Cukor

Peter H. Wiernik, MD, Doctor HC 
Cancer Research Foundation, Chappaqua, NY, USA

Janice P. Dutcher, MD
Cancer Research Foundation, Chappaqua, NY, USA

Morie A. Gertz, MD
Mayo Clinic, Department of Hematology, Rochester, MN, USA
 

Spans the range of hematologic neoplastic disorders from a clinical perspective

Integrates the history, epidemiology, pathology, pathophysiology, therapeutics, and supportive care of neoplastic hematopathology

Presented in an accessible and easy-to-read layout

Written by internationally renowned experts in the field