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Neuroimmunology, 1st ed. 2021 Multiple Sclerosis, Autoimmune Neurology and Related Diseases

Langue : Anglais

Coordonnateurs : Piquet Amanda L., Alvarez Enrique

Couverture de l’ouvrage Neuroimmunology

This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches.

Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentations in neuroimmunology, including pediatric demyelinating diseases.  These sections provide practical clinical information to improve the reader?s knowledge in this complex field. The chapters are written by world renown authors with extensive knowledge to help provide up to date information. The full scope of autoimmune neurology is discussed, which is a unique feature of this book.

Neuroimmunology serves as a resource for those in training including residents and fellows to provide clear clinical reasoning and background in a rapidly advancing field.


Part 1 Immunology, Pathophysiology and Immunotherapy
Introduction to Immunology and Overview of the Immune System (BBB, Lymphatics, innate and adaptive immune system)
Immunology of Multiple sclerosis (Role of B, T and innate immune system)
Pathology of Multiple sclerosis
Antibody pathogenesis and detection method for neuronal autoantibodies (Testing methods IFA, CBA, ELISA etc., (Synaptic vs intracellular antibodies in autoimmune/paraneoplastic disease)
Mechanisms and Principles of Immunotherapy

Part 2 Multiple Sclerosis
Natural history of MS (relapses/progressive MS)
Evolution of the diagnostic criteria in MS (MRI, CSF, OCT/VER)
Epidemiology/Demographics/Environmental effects of MS
Pediatric MS
Treatment of MS 
Trial design (ARR/MRI metrics/biomarkers)
Disease modifying treatments
Treatment selection and Treatment discontinuation

Part 3 Autoimmune Neurology
Autoimmune Encephalitis
Autoimmune Myelitis and Myelopathy
Autoimmune Epilepsy
Autoimmune Movement Disorders
Autoimmune Demyelinating disease: NMOSD and anti-MOG
Autoimmune Ophthalmologic disease
Autoimmune Neurology in Pediatrics (might need to include discussion on ADEM in this chapter)
Treatment Approaches in Autoimmune Neurology (Overall lack of clinical trials and barriers, Current treatment approach)

Part 4 Other CNS inflammatory diseases 
Neurorheumatology
Neurosarcoidosis
Vasculitis
Hypertrophic Pachymeningitis (To include a discussion on IgG-RD)
Role of infection and immunodeficiency in inflammatory disease
Role of Oncological disease in inflammatory disease (to include lymphoma, CLIPPERS, Erdheim Chester)

Amanda L. Piquet, MD

University of Colorado

School of Medicine

Aurora, CO

USA

 

Enrique Alvarez MD, PhD

University of Colorado

School of Medicine

Aurora, CO

USA


Focuses on various neuroinflammatory diseases, including multiple sclerosis, immune-mediated neurological diseases and autoimmune neurological disease

Reviews pathophysiology and treatment approaches

Provides neurologists and trainees a comprehensive resource to this rapidly growing field

Date de parution :

Ouvrage de 535 p.

17.8x25.4 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

121,31 €

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Date de parution :

Ouvrage de 535 p.

17.8x25.4 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

168,79 €

Ajouter au panier