Lavoisier S.A.S.
14 rue de Provigny
94236 Cachan cedex
FRANCE

Heures d'ouverture 08h30-12h30/13h30-17h30
Tél.: +33 (0)1 47 40 67 00
Fax: +33 (0)1 47 40 67 02


Url canonique : www.lavoisier.fr/livre/medecine/new-strategies-in-stroke-intervention/descriptif_2832902
Url courte ou permalien : www.lavoisier.fr/livre/notice.asp?ouvrage=2832902

0 article 

 Frais de port 0,01€*

Exclusivité web : à partir de 35 euros d’achat, frais de port à 1 centime pour les expéditions vers la France métropolitaine, la Suisse et l’UE avec Colissimo ou GLS

New Strategies in Stroke Intervention, 2010 Ionic Transporters, Pumps, and New Channels Contemporary Neuroscience Series

Langue : Anglais

Coordonnateur : Annunziato Lucio

Couverture de l’ouvrage New Strategies in Stroke Intervention

Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized. Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for curing stroke is far less understood than for many other normal and pathological conditions. New Strategies in Stroke Intervention: Ionic Channels, Pumps, and Transporters, analyzes the roles played by targets in stroke development and the potential action of drugs modulating these proteins. This book provides a groundbreaking review of these ionic channels, pumps, and transporters as regulators of neuronal ionic homeostasis, providing a better understanding of ischemic brain disorders and the new pharmacological avenues for a cure.

Basis of Ionic Dysregulation in Cerebral Ischemia.- Why have Ionotropic and Metabotropic Glutamate Antagonists Failed in Stroke Therapy?.- Mitochondrial Channels as Potential Targets for Pharmacological Strategies in Brain Ischemia.- Endoplasmic Reticulum Calcium Homeostasis and Neuronal Pathophysiology of Stroke.- The Na + /Ca 2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia.- The “Loop” Diuretic Drug Bumetanide-Sensitive Na + -K + -Cl - Cotransporter in Cerebral Ischemia.- The Na + /H + Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia.- The Na + /K + -ATPase as a Drug Target for Ischemic Stroke.- Acid-Sensing Ion Channels (ASICs): New Targets in Stroke Treatment.- Role of TRPM7 in Ischemic CNS Injury.- Subtypes of Voltage-Gated Ca 2+ Channels and Ischemic Brain Injury.- The Diverse Roles of K + Channels in Brain Ischemia.- Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic Stroke.
Useful for researchers working in the field of stroke research, and any student interested in the physiological, pathophysiological, and pharmacological features of stroke damage Analyzes the roles played by targets in stroke development and the potential action of drugs modulating these proteins Full color throughout Includes supplementary material: sn.pub/extras

Date de parution :

Ouvrage de 254 p.

15.5x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

116,04 €

Ajouter au panier

Date de parution :

Ouvrage de 254 p.

15.5x23.5 cm

Sous réserve de disponibilité chez l'éditeur.

158,24 €

Ajouter au panier