Parkinson’s Disease, Softcover reprint of the original 1st ed. 1977 Neurophysiological, Clinical, and Related Aspects Advances in Experimental Medicine and Biology Series, Vol. 90

These Proceedings are the outcome of the First Tarbox Parkinson's Disease Symposium held October 14-16, 1976, at the South Park Inn in Lubbock, Texas. The Symposium was sponsored by the Department of Pharmacology and Therapeutics and the Tarbox Parkinson's Disease In­ stitute of the Texas Tech University School of Medicine at Lubbock. The Tarbox Parkinson's Disease Institute was established in 1973 with funds appropriated by the State of Texas and is dedicated to re­ search, patient care, and educational activities related to Parkinson's disease. The Institute is named after Mr. Elmer L. Tarbox, who recently served the Lubbock area as a Representative to the Texas Legislature, and is himself a parkinsonian patient. Mr. and Mrs. Tarbox attended the Symposium as honored guests. The First Tarbox Parkinson's Disease Symposium was devoted to both basic and clinical aspects of Parkinson's disease, with an emphasis on discussion of drug therapy. This discussion focused not only on readily available drugs such as levodopa, but also on new investigational drugs such as bromocriptine. Thanks are especially due to Thelma Saunders and the office staff of the Department of Pharmacology and Therapeutics, Texas Tech Univer­ sity School of Medicine, for their excellent service in producing camera-ready copy for the Publisher. Thanks are also due to Fathy S. Messiha, Program Chairman, to the other committee members, and to the staff of the Office of Continuing Education and Faculty Development. The Symposium could not have succeeded without their help.

Invited Speakers.- Historical Aspects and Frontiers of Parkinson’s Disease Research.- Recent Advances in the Biochemical Pharmacology of Extrapyramidal Movement Disorders.- Treatment of Parkinsonism.- Parkinsonism and Epilepsy.- Neurophysiology of Movement Disorders.- Problems in the Treatment of Parkinsonism.- New Approaches in the Management of Hyperkinetic Movement Disorders.- Submitted Short Communications.- The On-Off Effect in Parkinson’s Disease Treated with Levodopa with Remarks Concerning the Effects of Sleep.- Adenylate Cyclase from Various Dopaminergic Areas of the Brain and the Action of Loxapine.- Pharmacopsychiatry and Iatrogenic Parkinsonism.- Comparison of Lithium and Haloperidol Therapy in Gilles de la Tourette Syndrome.- Dopamine Receptors Hypersensitivity: Further Confirmation Following Drug Abuse Model.- L-Dopa-Induced Hypotension: Depression of Spinal Sympathetic Neurons by Release of 5-Hydroxytryptamine.- Antinociciptive effect of Dopaminergic Neurotransmission Evoked by Mesencephalic Stimulation on Spinal Interneuronal Activity in Cats.- The Parkinsonian Syndrome and its Dopamine Correlates.- CNS Compensation to Dopamine Neuron Loss in Parkinson’s Disease.- Brain Dopamine Turnover and theRelief of Parkinsonism.- Evaluation of Experimental Anticholinergic Drug, Elantrine, in Treating the Tremor of Parkinsonism.- Maternally Determined Susceptibility to D-Amphetamine-Induced Stereotypyin Rats.- Postmenopausal Parkinsonism: BrainIron Overload?.- Failure of L-Dopato Relieve Activated Rigidity in Parkinson’s Disease.- SubjectInde.