Description
Pathogenesis, Treatment and Prevention of Leishmaniasis
Coordinators: Samant Mukesh, Chandra Pandey Satish
Language: English
Subjects for Pathogenesis, Treatment and Prevention of Leishmaniasis:
Keywords
Animal model; Antileishmanial drugs; Apoptosis; Apoptotic pathway; Artificial intelligence; Biomarkers; Combinatorial therapy; Computational approach; Cutaneous leishmaniasis; Drug discovery; Drug repurposing; Drug resistance; Drug target; Drug targets; Endo G; Epidemiology; Essential oil; Evolutionary relationships; High resolution melting; Immune response; Immunity; Immunological determinants; Infection; Interferon-?; Kala-azar; Leishmania; Leishmania diagnosis; Leishmaniasis; Lipid nanocapsules; Liposomes; Medicinal plants; Metacaspases; Microarray; Molecular methods; Mucocutaneous leishmaniasis; Multilocus enzyme electrophoresis; Nanotechnology; Nanotubes; Nanovaccines; Parasitological; Pharmacophore; Prophylactic; Secondary metabolites; Serological; Therapy; Toxicity; Transcriptomic; Vaccine; Virtual screening; Visceral leishmaniasis; Wolbachia
280 p. · 15x22.8 cm · Broché
Résumé
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Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis.
1. An overview of leishmaniasis: historical aspects and future perspectives 2. Leishmaniasis: symptoms, disease, and clinical picture 3. Traditional and advanced strategies for the treatment 4. Drug development and resistance in Leishmaniasis 5. Vaccination studies to cure Leishmania Infection 6. Strategies of immune evasion by Leishmania 7. Cell death in Leishmania 8. Stress responses in Leishmania 9. Different in vivo models for the discovery and utility of drug targets and vaccine candidates against leishmaniasis 10. Recent advances in the diagnostic methods of leishmaniasis
Satish Chandra Pandey is a researcher whose area of expertise is microbiology, molecular parasitology and immunology specifically looking at attenuated vaccine and drug target against protozoan parasite Leishmania. He has completed his M.Sc. in Microbiology From G.B.P.U&T Pantnagar U.S Nagar India. He joined Kumaun University a couple of years ago as a Research Assistant at Cell and Molecular Biology Laboratory, department of Zoology Kumaun University SSJ campus, Almora, (Uttarakhand), India. Currently he is pursuing Ph.D in Biotechnology and also working as a Guest Faculty at department of Zoology Kumaun University SSJ campus, Almora, (Uttarakhand). His Ph.D work is focused on the identification of drug targets and development of live attenuated vaccine against lieshmaniasis. He has published various research articles and book chapters in very high rated international journals.
- Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment
- Discusses novel approaches to study parasite infection and treatment
- Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies
