Progressive Brain Disorders in Childhood

Progressive neurodevelopmental disorders that affect the development of the infant brain can have detrimental impacts on a range of cognitive and emotional behaviors. The identification and management of these disorders can be challenging for neurologists, pediatricians and other healthcare professionals who encounter these conditions in their practices. This book is essential for teaching medical practitioners how to promptly identify neurological regression during childhood development and investigate disorders in sufficient depth to be able to arrive at a precise syndromic diagnosis, plan appropriate management for the patient, and offer advice to caregivers. The text provides a platform for clinicians - new and experienced - to expose their knowledge gaps in the field of neurodegenerative and related disorders. Individual disorders are analyzed by age of onset, with attention given to disorders present in utero, in the newborn, in the infant, and the adolescent, making this a practical and comprehensive guide for any healthcare professional.

Part I. Introduction; Section 1. Introduction; Part II. Rise and Decline of the Child; Section 2. Human Neurological Development; Part III. Mechanisms of Neurological Loss of Function; Section 5. Degeneration in the Central Nervous System; Part IV. Neurodegenerative and Other Progressive Disorders in Childhood; Section 7. Progressive in Utero Disorders; Part V. Regression in Other Neurological and Psychiatric Disorders; Section 12. Epilepsy; Part VI. Induced Regression; Section 21. Loss of Sensory Organs.

Juan M. Pascual is a Professor at the Eugene McDermott Center for Human Growth and Development, and in the Departments of Neurology and Neurotherapeutics, Physiology and Pediatrics, at the University of Texas Southwestern Medical Center, Dallas.