Neonatal Pulmonary Hypertension, An Issue of Clinics in Perinatology
The Clinics: Orthopedics Series

In this issue of Clinics in Perinatology, guest editors Drs. Satyanarayana Lakshminrusimha and Steve Abman bring their considerable expertise to the topic of Neonatal Pulmonary Hypertension. About one in every 1,250 newborns develop neonatal pulmonary hypertension, and about 25% of survivors will have developmental delays, hearing problems, and/or functional disabilities. In this issue, top experts provide updates to the perinatologist on managing this condition to improve patient outcomes.

• Contains 15 relevant, practice-oriented topics including early pulmonary hypertension in preterm neonates; targeted neonatal echocardiography in the management of neonatal pulmonary hypertension; bronchopulmonary dysplasia and pulmonary hypertension; co-morbidities and late outcomes in neonatal pulmonary hypertension; management of PPHN in resource-limited settings; and more.
• Provides in-depth clinical reviews on neonatal pulmonary hypertension, offering actionable insights for clinical practice.
• Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Pulmonary Vascular Regulation in the Fetal and Transitional Lung
Pathogenesis and Physiologic Mechanisms of Neonatal Pulmonary Hypertension: Preclinical Studies
Targeted Neonatal Echocardiography in the Management of Neonatal Pulmonary Hypertension
Oxygen Targets in Neonatal Pulmonary Hypertension: Individualized, "Precision[1]Medicine” Approach
Inhaled Nitric Oxide in Neonatal Pulmonary Hypertension
Targeted Therapies for Neonatal Pulmonary Hypertension: Beyond Nitric Oxide
Asphyxia, Therapeutic Hypothermia, and Pulmonary Hypertension
Congenital Diaphragmatic Hernia: Pulmonary Hypertension and Pulmonary Vascular Disease
Early Pulmonary Hypertension in Preterm Infants
Pulmonary Hypertension in Established Bronchopulmonary Dysplasia: Physiologic Approaches to Clinical Care
Pulmonary Hypertension in Developmental Lung Diseases
Etiology, Diagnosis and Management of Persistent Pulmonary Hypertension of the Newborn in Resource-limited Settings
Randomized Controlled Trials of Pulmonary Vasodilator Therapy Adjunctive to Inhaled Nitric Oxide for Persistent Pulmonary Hypertension of the Newborn: A Systematic Review
Comorbidities and Late Outcomes in Neonatal Pulmonary Hypertension