Stem Cells and Neurodegenerative Diseases

This book explores the potentiel of stem cells for ameliorating the quality of life of patients with neurological and neurodegenerative diseases. It discusses results of pre-clinical investigations and case studies on the effects of stem cell transplantation on cell death, to promote/stimulate neuroprotection after brain and spinal cord injury through trophic support, cell replacement and remyelination. It covers the maintenance of the balance between stem cells and their progenitors within their niche, both under normal and degenerative processes, ischemic stroke, multiple sclerosis, and brain tumor.

Stem Cells as a Source for Cell Therapy in Parkinson's Disease. The use of stem cells in treating Huntington’s disease: state of research and prospects for future treatments. Stem Cell Transplantation Strategies After Spinal Cord Injury. Role of endogenous neural precursor cells in Multiple Sclerosis. Stem cells and Alzheimer’s disease. Cell Therapies for Ischemic Stroke. Immune response to intracerebral transplantation: particular properties of stem cells. Glioma stem cells: the brain behind the tumor? The future of induced pluripotent stem cells in brain regenerative medicine.

Lescaudron, Laurent; Rossignol, Julien; Dunbar, Gary L.