Description
The Living Brain and Alzheimer’s Disease, 2004
Research and Perspectives in Alzheimer's Disease Series
Language: EnglishSubject for The Living Brain and Alzheimer’s Disease:
Publication date: 04-2014
180 p. · 15.5x23.5 cm · Paperback
Publication date: 06-2004
180 p. · 24.8x16.5 cm · Hardback
Description
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From large cross-sectional studies of autopsy material, it seems as if a time course of Alzheimer's Disease, at least on average, can be mapped out: a pattern of hierarchical vulnerability for neuronal loss and neurofibrillary tangles beginning in medial temporal lobe structures proceeding through association areas. Plaques follow their own temporal course, with widespread cortical deposits occurring even early in a disease process. The whole process may well take twenty years, the first half of which may be without overt symptoms.
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