Treatable and Potentially Preventable Dementias

The first comprehensive and authoritative book covering the basis for the joint prevention of stroke and the management, delay, or prevention of some dementias. Engaging with the concept of cerebrovascular disease as asymptomatic, with overwhelming evidence that major dementias involve a vascular component, ranging from 60 per cent in frontotemporal dementia to 80 per cent in Alzheimer disease - doubling the chances of silent brain pathology manifesting as dementia. Beginning with a review of the basics, describing typical patients and presentations and providing clear guidelines in diagnoses, management, and prevention, this vital guide is invaluable for physicians dealing with cognitive impairments, including family physicians, psychiatrists, internists, geriatricians and neurologists, worldwide. This book provides a new, coherent and promising approach, filling the gap between what is known and what is applied, offering a great opportunity for appropriate interventions and treatments that make a difference. Improving outcomes, beginning now.

1. Pathophysiology and epidemiology Mahmoud Reza Azarpazhooh and Vladimir Hachinski; 2. Diagnosis of potentially preventable dementias José G. Merino and Clinton B. Wright; 3. The brain at risk stage Mahmoud Reza Azarpazhooh and Vladimir Hachinski; 4. The patient with cognitive impairment Krister Håkansson, Miia Kivipelto and Tiia Ngandu; 5. Cognitive decline in transient ischemic attacks or minor strokes Antonia Nucera, Mahmoud Reza Azarpazhooh and Vladimir Hachinski; 6. The stroke patient and cognition Michael Brainin and Yvonne Teuschi; 7. Reversible dementias Lawrence S. Honig; 8. Prevention of dementia J. David Spence.

Vladimir Hachinski is the Distinguished University Professor at the University of Western Ontario, Canada. He trained in neurology and research in Montreal, Toronto, London, UK and Copenhagen. Professor Hachinski introduced the concepts brain at risk, multi-infarct dementia, leukoaraiosis, vascular cognitive impairment and his eponymic ischemic scale. Professor Hachinski has co-authored 17 books and over 800 publications, was the Editor of Stroke and President of the World Federation of Neurology. His awards include the International BIAL Merit Award in Medical Sciences and the Prince Mahidol Award.