Adenomatous Polyps of the Colon, Softcover reprint of the original 1st ed. 1990 Pathobiological and Clinical Features

A consolidation of the information that has accumulated on the basic science and clinical aspects of APs of the colon, much of it inspired by the realization that most colorectal carcinomas seem to arise in such polyps. The author synthesizes the data, with special emphasis on implications for patie

Normal Colon.- A. Anatomic Considerations.- B. Histology.- Pathology.- A. General Prevalence and Anatomic Distribution.- B. Gross Appearance.- C. Microscopic Features.- D. Differential Diagnosis.- E. The Diminutive Polyp.- F. Other Characteristics of Polyps.- G. Histogenesis of Polyps.- Adenomatous Polyposes.- A. Familial Polyposis Coli and Gardner’s Syndrome.- B. Other Adenomatous Polyposis Syndromes.- C. The Genetics of Adenoma Transmission.- Malignant Potential of Adenomatous Polyps.- A. Association of Polyps and Carcinomas.- B. Histological Evidence of Malignant Transformation.- C. Adenomatous Remnants in Carcinomas.- D. Epidemiological Evidence and Etiological Factors.- E. Findings in Experimental Animals.- F. Alternate Hypotheses of Carcinogenesis.- G. Conclusions.- Detection and Management.- A. Screening, Diagnostic, and Surveillance Techniques.- B. The Malignant Polyp.- C. Endoscopic Polypectomy.- D. Postpolypectomy Surveillance Recommendations.- E. The National Polyp Study.- F. Polyp Registries.- Conclusions.- Glossary and Abbreviations.