Introduction to Cell Mechanics and Mechanobiology

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Language: English
Cover of the book Introduction to Cell Mechanics and Mechanobiology

Keywords

Mechanosensitive Ion Channels; Intermediate Filament; cell mechanics; Myosin Heads; mechanobiology; Primary Cilium; cell biology; Persistence Length; molecular biology; Micropipette Aspiration; cell signaling; Actin Filament; experimental biology; Liquid Drop Model; modern genetics; Fluid Shear Stress; bioinformatics; Areal Strain; systems biology; biomechanics; Green Lagrange Strain; rigid-body mechanics; Strain Energy; free-body diagram; Microcanonical Ensemble; deformable-body mechanics; Free Body Diagram; strain; Energy Density; stress; Ideal Chain; torsion; Strain Energy Density; kinematics; Tensegrity Structures; equilibrium; Contour Length; constitutive equation; Cellular Solids; large deformation mechanics; Red Blood Cell’s Cytoskeleton; fluid mechanics; Equibiaxial Tension; fluid statics; Stress Fiber; Newtonian fluids; TFM; non-Newtonian behavior; Navier-Stokes equation; rheological analysis; complex moduli; power laws; dimensional analysis; Buckingham Pi Theorem; statistical mechanics; internal energy; potential energy; entropy; free energy; thermodynamics; thermodynamic system; canocical ensemble; Boltzmann's law; random walks; cellular micromanipulation; cell force; deformation; deformation analysis; cellular polymers; biopolymer structure; polymerization kinetics; freely jointed chain; worm-like chain; polymer networks; cellular solids theory; affine network; biomechanical function; cytoskeletal structure; actin; myosin; filopedia; membrane biology; membrane mechanics; adhesion; Bell model; Bell equation; migration; contraction; Hill equation; cellular mechanotransduction; mechanical signal; mechanosensing organelle; membrane; intracellular signaling

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400 p. · 21x28 cm · Paperback

Introduction to Cell Mechanics and Mechanobiology is designed for a one-semester course in the mechanics of the cell offered to advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering. It teaches a quantitative understanding of the way cells detect, modify, and respond to the physical properties within the cell environment. Coverage includes the mechanics of single molecules, polymers, polymer networks, two-dimensional membranes, whole-cell mechanics, and mechanobiology, as well as primer chapters on solid, fluid, and statistical mechanics, and cell biology.

Introduction to Cell Mechanics and Mechanobiology is the first cell mechanics textbook to be geared specifically toward students with diverse backgrounds in engineering and biology.

Part I. Principles
1. Cell Mechanics as a Framework
2. Fundamentals of Cell Biology
3. Solid Mechanics Primer
4. Fluid Mechanics Primer
5. Statistical Mechanics Primer

Part II. Practices
6. Cell Mechanics in the Laboratory
7. Mechanics of Cellular Polymers
8. Polymer Networks and the Cytoskeleton
9. Mechanics of the Cell Membrane
10. Adhesion, Migration, and Contraction of the Cell
11. Mechanotransduction and Intracellular Signaling

Christopher R. Jacobs, Hayden Huang, Ronald Y. Kwon