Bioactive Lipids

In Bioactive lipids, Anna Nicolaou and George Kokotos have brought together an international team of authors to discuss the nomenclature, structures, biochemistry, pharmacology and recent developments in the main classes of bioactive lipids. These lipids are essential components of the cell membrane and play many dynamic roles in mediating and controlling a wide array of cellular activities including membrane structure and organization, metabolic and gene regulation, protein structure and function, energy production, and signalling pathways.

The lipid interests of scientists in the pharmaceutical and food industries are converging as the broader significance of bioactive lipids is increasingly recognized. Lipids and lipid-metabolizing enzymes are targeted for the development of new drugs. Meanwhile, functional foods, nutraceuticals and supplements already have lipids as major active ingredients. The food industry will progress from simply using lipids as ingredients, to the formulation of products that influence the synthesis, metabolism and effects of bioactive lipids in the body. These advances in applied lipid biochemistry will build on the fundamental research of lipid scientists in universities worldwide, such as those scientists contributing to Bioactive lipids.

Fatty acids; Diacylglycerols; Phosphoinositides; Lysolipids: Sphingosine 1-phosphate and lysophosphatidic acid; Plasmalogens, PAF and other ether lipids; Ceramides; Glycosphingolipids; Prostanoids; Leukotrienes and lipoxins; Endocannabinoids; Isoprostanes.

Anna Nicolaou, University of Bradford, UK.
George Kokotos, University of Athens, Greece.