Cell Press Reviews: Stem Cells to Model and Treat Disease
Cell Press Reviews Series

Cell Press Reviews: Stem Cells to Model and Treat Disease informs, inspires, and connects stem cell researchers and clinicians at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publication offers a broad view of some of the most compelling topics in stem cell research including:

• Safety and efficacy of stem cell treatments
• Stem-cell-based organ regeneration
• Integrating stem cells into personalized drug discovery
• Using pluripotent stem cells for treating neurological disease
• Engineering hematopoietic stem cells for innovative therapies

Contributions come from leading voices in the field, including: - Shinya Yamanaka, Recipient of the 2012 Nobel Prize for Physiology or Medicine, Recipient of the 2012 Millennium Technology Prize, Professor and Director of the Center for iPS Cell Research and Application at Kyoto University, Senior Investigator at the Gladstone Institute of Cardiovascular Disease, L.K. Whittier Foundation Investigator in Stem Cell Biology and Professor at the University of California, San Francisco - George Q. Daley, Samuel E. Lux IV Professor of Hematology/Oncology at Harvard Medical School and Director for the Stem Cell Transplantation Program at Boston Children?s Hospital - Irving Weissman, Member of National Academy of Sciences, Virgina & D.K Ludwig Professor for Clinical Investigation in Cancer Research, and Director for Institute of Stem Cell Biology and Regenerative Medicine at Stanford University of Medicine

Cell Press Reviews: Stem Cells to Model and Treat Disease is part of the Cell Press Reviews series, which features reviews published in Cell Press primary research and Trends reviews journals.

1) Stem cell therapies could change medicine... if they get the chance; Irving Weissman; Cell Stem Cell 2) Why is it taking so long to develop clinically competitive stem cell therapies for CNS disorders? Olle Lindvall; Cell Stem Cell 3) Assessing the safety of stem cell therapeutics; Chris E.P. Goldring, Paul A. Duffy, Nissim Benvenisty, Peter W. Andrews, Uri Ben-David, Rowena Eakins, Neil French, Neil A. Hanley, Lorna Kelly, Neil R. Kitteringham, Jens Kurth, Deborah Ladenheim, Hugh Laverty, James McBlane, Gopalan Narayanan, Sara Patel, Jens Reinhardt, Annamaria Rossi, Michaela Sharpe and B. Kevin Park; Cell Stem Cell 4) The promise and perils of stem cell therapeutics; George Q. Daley; Cell Stem Cell 5) Reprogramming cellular identity for regenerative medicine; Anne B.C. Cherry and George Q. Daley; Cell 6) Cardiac stem cell therapy and the promise of heart regeneration; Jessica C. Garbern and Richard T. Lee; Cell Stem Cell 7) Next-generation regenerative medicine: Organogenesis from stem cells in 3D culture; Yoshiki Sasai; Cell Stem Cell 8) Induced pluripotent stem cells: past, present, and future; Shinya Yamanaka; Cell Stem Cell 9) Remodeling neurodegeneration: Somatic cell reprogramming-based models of adult neurological disorders; Liang Qiang, Ryousuke Fujita and Asa Abeliovich; Neuron 10) Therapeutic translation of iPSCs for treating neurological disease; Diana X. Yu, Maria C. Marchetto and Fred H. Gage; Cell Stem Cell 11) Modeling human disease with pluripotent stem cells: From genome association to function; Florian T. Merkle and Kevin Eggan; Cell Stem Cell 12) How can human pluripotent stem cells help decipher and cure Huntington's disease? Anselme Perrier and Marc Peschanski; Cell Stem Cell 13) Integrating human pluripotent stem cells into drug development; Sandra J. Engle and Dinesh Puppala; Cell Stem Cell 14) Process engineering of human pluripotent stem cells for clinical application; Margarida Serra, Catarina Brito, Cláudia Correia and Paula M. Alves; Trends in Biotechnology 15) Mesenchymal stem cells: Therapeutic outlook for stroke; Osamu Honmou, Rie Onodera, Masanori Sasaki, Stephen G. Waxman and Jeffery D. Kocsis; Trends in Molecular Medicine 16) The potential of stem cells as an in vitro source of red blood cells for transfusion; Anna Rita Migliaccio, Carolyn Whitsett, Thalia Papayannopoulou and Michel Sadelain; Cell Stem Cell 17) Hematopoietic-stem-cell-based gene therapy for HIV disease; Hans-Peter Kiem, Keith R. Jerome, Steven G. Deeks and Joseph M. McCune; Cell Stem Cell 18) Stem cells in translation; Cell

• Provides timely overviews on a wide range of stem cell applications
• Offers insight from experts on the key opportunities and challenges facing the field
• Features reviews on genetic, cellular, and molecular aspects of stem-cell-based applications
• Includes articles originally published in Cell, Cell Stem Cell, Neuron, Trends in Molecular Medicine, and Trends in Biotechnology