Cell Signaling & Molecular Targets in Cancer, 2012

Acknowledgement.- GRB2 Signaling as a Molecular Target for Cancer.- Human arylamine N-acetyltransferase 1 : from drug metabolism to drug target.- Targeting Argininosuccinate Synthetase in Cancer Therapy.- Parathyroid hormone-related peptide signaling in cancer.- Signaling Molecules as Selective Targets for Therapeutic Strategies in Multiple Myeloma.- Role of Bile Acids in Carcinogenesis of Gastrointestinal Tract.- AIB1: A Transcriptional Coactivator which Integrates Signaling Crosstalk in Cancer Cells.- Rational Design of DNA Anti-cancer Agent that Targets Signal Transducer and Activator of Transcription 3 (Stat3) for Cancer Therapy.- Estrogen Receptor Signaling in Lung Cancer.- Microparticle Dissemination of Biological Activities: Implications for Cancer Biology.- Protein Kinase D Signaling in Cancer.- Cell Signaling and Cancer: Integrated, Fundamental Approach Involving Electron Transfer,Reactive Oxygen Species and Antioxidants.- PPARg, Thiazolidinediones, Lung Cancer.- Targeting Signal Transducer and Activator of Transcription (STAT) for Anti-Cancer Therapy.- Index  

Identifies various signaling molecules like GRB2 growth factors, A1B1, STAT, TGFß

Provides a critical assessment of surrogate markers involved in the emergence and progression of cancer

Covers the basic principle that drive oncogenesis and pharmacological interventions that lead to therapies