Description
Extrasynaptic GABAA Receptors, Softcover reprint of the original 1st ed. 2014
The Receptors Series, Vol. 27
Coordinators: Errington Adam C., Di Giovanni Giuseppe, Crunelli Vincenzo
Language: EnglishSubjects for Extrasynaptic GABAA Receptors:
Support: Print on demand
295 p. · 15.5x23.5 cm · Hardback
Description
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A brief introduction to extrasynaptic GABAA receptors and ‘tonic’ GABAA receptor mediated inhibition in physiology and disease.- Extrasynaptic GABAA receptors: subunit composition, distribution, and regulation.- Biophysical properties of recombinant 2- AND δ- subunit containing GABAA receptors.- The pharmacology of extrasynaptic GABAA receptors.- Neurosteroids and extrasynaptic GABAA receptors.- Sources of GABA that activate extrasynaptic GABAA receptors.- Modulation of Extrasynaptic GABAA Receptors by G-protein-coupled Receptors.- Extrasynaptic GABAA receptors and tonic inhibition in spinal cord.- The role of peri-synaptic GABA receptors after stroke.- The role of extrasynaptic GABAA receptors in focal epilepsy.- Gain-of-Function of Thalamic Extrasynaptic GABA-A Receptors in Typical Absence Seizures.- GABAergic control of the hypothalamic-pituitary-adrenal (HPA) axis: role of extrasynaptic GABAA receptors.- Tonic GABAA receptor mediated inhibition in Fragile-X Syndrome: A cause of dysfunction or a pathway for a cure?