Description
G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis
Progress in Molecular Biology and Translational Science Series
Author: TAO Ya-Xiong
Language: EnglishSubjects for G Protein-Coupled Receptors in Energy Homeostasis and...:
Keywords
G protein-coupled receptor; Energy homeostasis; Neuropeptides; Gastrointestinal peptide; Pancreatic peptide; Genetics; Ghrelin; Ghrelin receptor; Glucose homeostasis; Lipid metabolism; Antagonist; Obesity; Diabetes; Major gene; Polygene; Effect size; Weight regulation; Estradiol; Fat distribution; Visceral fat; Energy balance; Genomic; Nongenomic; Estrogen nuclear receptors; Adipogenesis; Lipoplysis; CCK1 receptor; CCK2 receptor; Meal size; Inter-meal interval; Enteric nervous system; Adipose tissue; Adiponectin; Adipokine; AdipoR1; AdipoR2; Metabolism; Bombesin; Gastrin-releasing peptide; Meal size; Intermeal interval; Enteric nervous system
400 p. · 15x22.8 cm · Hardback
Description
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Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans.
G Protein-coupled receptors in energy homeostasis and obesity: An introduction
Y. Tao
Ghrelin receptor in energy homeostasis and obesity pathogenesis
W. Zhang
Obestatin receptor in energy homeostasis and obesity pathogenesis
J. Zhang
Melanocortin-3 receptor in energy homeostasis and obesity pathogenesis
A. Butler
Melanocortin-4 receptor in energy homeostasis and obesity pathogenesis
A. Hinney
G protein-coupled estrogen receptor in energy homeostasis and obesity pathogenesis
H. Shi
Relaxin-3 receptor in energy homeostasis and obesity pathogenesis
C. Liu
Cholecystokinin receptor in energy homeostasis and obesity pathogenesis
A. Sayegh
Adiponectin receptor in energy homeostasis and obesity pathogenesis.
B. Akingbemi
- Subject matter: obesity is an epidemic and G protein-coupled receptors are promising drug targets, with significant potential as new anti-obesity drugs
- Chapters are written by leading experts