Management of Treatment-Resistant Major Psychiatric Disorders

Although there are a variety of textbooks and manuals of psychiatric disorders, few have focused on the management of treatment-resistant patients. Those that exist have largely focused on treatment-resistant depression and even these are now largely outdated. Because psychiatrists and other mental health care professionals increasingly manage patients who fail treatment from family practitioners and other non-psychiatric specialists, a single practical volume summarizing the evidence-based medicine as well as the art of managing treatment-resistant patients is a much needed volume for practitioners, psychiatry residents and other mental health workers. Most importantly, both psychopharmacological and psychotherapeutic interventions will be included, a shortcoming of many previous volumes. "Management of Treatment Resistant Major Psychiatric Disorders" contains chapters authored by leaders in the field on the management of the major treatment resistant psychiatric disorders.

Chapter 1. The Problem of Treatment-Resistant Major Psychiatric Disorders. Charles B. Nemeroff and Patricio Riva Posse. Chapter 2. Management of Treatment-Resistant Depression: Psychopharmacology and Psychotherapy. Michael E. Thase and K. Ryan Connolly. Chapter 3. Management of Treatment-Resistant Depression - Somatic-Non-pharmacological Strategies. Paul E. Holtzheimer. Chapter 4. Management of Treatment-Resistant Bipolar Disorder. Mark A. Frye. Chapter 5. Management of Treatment-Resistant Panic Disorder. Robert Bruce Lydiard. Chapter 6. Management of Treatment-Resistant Post-Traumatic Stress. Disorder. Dan J. Stein and Kerry-Ann Louw. Chapter 7. Management of Treatment-Resistant Social Anxiety Disorder. Eric Bui and Mark H. Pollack. Chapter 8. Management of Treatment-Resistant Generalized Anxiety Disorder. Victoria Osman-Hicks, John Potokar, and David J. Nutt. Chapter 9. Management of Treatment-Resistant Obsessive-Compulsive Disorder. Robert Hudak, Priya Gopalan, and Darin D. Dougherty. Chapter 10. Management of Treatment-Resistant Anorexia Nervosa. Enrica Marzola, Mary Ellen Trunko, Emily Grenesko-Stevens and Walter H. Kaye. Chapter 11. Management of Treatment-Resistant Schizophrenia. Jacob S. Ballon and Jeffrey A. Lieberman. Chapter 12. Management of Treatment-Resistant Substance and Alcohol Abuse. Kathleen T. Brady. Chapter 13. Management of Treatment-Resistant Personality Disorders. Glen O. Gabbard. Chapter 14. Management of Treatment-Resistant Insomnia. Karl Doghramji and Charles F. Reynolds III. Chapter 15. Management of Treatment-Resistant Childhood Disorders. Karen Dineen Wagner.

Dr. Nemeroff's research has concentrated on the biological basis of the major neuropsychiatric disorders, including affective disorders, schizophrenia, and anxiety disorders. His clinical research is focused on the use of genetic, neuroendocrine, neuroimaging and neurochemical methods to comprehensively understand the pathophysiology of depression. In recent years he has uncovered the neurobiological mechanisms that mediate the increased risk for depression in victims of child abuse. He has also contributed to seminal findings in the burgeoning area of research concerning the relationship of depression to cardiovascular disease.