Mitochondria and Cancer, 2009

Coordinators: Singh Keshav, Costello Leslie

Language: English

Approximative price 147.88 €

In Print (Delivery period: 15 days).

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289 p. · 15.5x23.5 cm · Paperback

An exhaustive analysis of the role of mitochondria in cancer, this book surveys the Warburg Hypothesis, mitochondrial structure and function, and then outlines the metabolic and molecular alterations in mitochondria that are associated with human cancer.

Mitochondria and Cancer.- Warburg and his Legacy.- The Lipogenic Switch in Cancer.- Citrate Metabolism in Prostate and Other Cancers.- Integration of Genetic, Proteomic, and Metabolic Approaches in Tumor Cell Metabolism.- Mitochondrial Respiration and Differentiation.- Integration of Energy Metabolism and Control of Apoptosis in Tumor Cells.- Energy Generating Pathways and the Tumor Suppressor p53.- Mitochondrial Tumor Suppressors.- Mitochondria in Hematology.- Mitochondria and Oncocytomas.- Mitochondria as Targets for Cancer Therapy.- Reversing the Warburg Effect: Metabolic Modulation as a Novel Cancer Therapy.- Mitochondrial Nanotechnology for Cancer Therapy.

Aims to provide a comprehensive analysis of the role mitochondria play in carcinogenesis

Will also provide up to date mitochondrial therapeutic approaches for treatment of cancer