Nutraceuticals and Health
Review of Human Evidence
Nutraceuticals Series

Although health claims for nutraceuticals range from the fantastic to the sublime, most of these claims are based on cell culture studies and have not been validated in humans, making them inadequate for public health recommendations. Focusing on human population-based research (epidemiology studies), Nutraceuticals and Health: Review of Human Evidence explores the role of nutraceuticals in human health, disease prevention, health promotion, and as an adjunct to disease treatment.

The editors and their team of recognized experts deliver a comprehensive scientific review of the latest research. The book opens with a general background of nutraceuticals and human health, then covers health and disease areas such as cancer, lipidermia and cardiovascular disease, metabolic syndrome with obesity, diabetes and hypertension, respiratory health, the gut microbiome, and cognitive decline. It then concludes by addressing the methodological issues that must be addressed in the conduct of epidemiological research on nutraceuticals in health and disease.

Although nutraceuticals hold significant promise in alleviating the suffering from disease, for this potential to be fulfilled, much more research is needed to document safety and disease risks in humans. Addressing important knowledge gaps, the book includes cutting-edge summaries that highlight both the biological and epidemiological findings of relevant studies of nutraceuticals in health and disease. Taking an unusual, yet crucial epidemiological focus, it examines whether, and what kinds of, evidence exist to support a role for nutraceuticals in disease risk, prevention, and treatment.

Introduction. Background to Nutraceuticals and Human Health. Cancer. Clinical Trials of Dietary Supplements and Cancer. Curcumin in Human Cancer Prevention and Treatment. Cancer Prevention Potential of Diet and Dietary Supplements in Epigenome Modulation.. Lipidemia and Cardiovascular Diseases. Role of Dietary Supplements in LDL Cholesterol Lowering.Nutraceuticals and Atherosclerosis: Human trials.. Nutraceuticals in Cardiovascular Disease: Mechanisms and Applications. Metabolic Syndrome: Obesity, Diabetes and Hypertension. Potential of Nutraceuticals against Obesity Complications. The Role of Nutraceutical Supplements in the Prevention and Treatment of Hypertension.. Nutraceuticals in the Treatment of Metabolic Syndrome. Medicinal Herbs and Dietary Supplements in Diabetes Management. Respiratory Health. Nutrients for Optimal Lung Function. Gut Microbiome. Nutraceutical-Gut Microbiome Interactions in Human Disease. Metabolic and Potential Health Benefits of Nutraceuticals on Gut Micorbiome. Cognitive decline & Neurodegeneration. Nutraceuticals in the Prevention of Cognitive Decline. Nutraceuticals in the Prevention or Treatment of Parkinson's Disease. Dietary Supplements and other Alternative Substances for the Treatment of Multiple Sclerosis.. Methodological Issues. Methodological Issues Conducting Epidemiological Research on Nutraceuticals..