Peroxisomes and their Key Role in Cellular Signaling and Metabolism, Softcover reprint of the original 1st ed. 2013
Subcellular Biochemistry Series, Vol. 69

Language: English

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Peroxisomes and their Key Role in Cellular Signaling and Metabolism
Publication date:
Support: Print on demand

158.24 €

In Print (Delivery period: 15 days).

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Peroxisomes and their Key Role in Cellular Signaling and Metabolism
Publication date:
350 p. · 15.5x23.5 cm · Hardback
Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism. In recent years it has become increasingly clear that peroxisomes are involved in a range of important cellular functions in almost all eukaryotic cells. In higher eukaryotes, including humans, peroxisomes catalyze ether phospholipids biosynthesis, fatty acid alpha-oxidation, glyoxylate detoxification, etc, and in humans peroxisomes are associated with several important genetic diseases. In plants, peroxisomes carry out the fatty acid beta-oxidation, photorespiration, metabolism of ROS, RNS and RSS, photomorphogenesis, biosynthesis of phytohormones, senescence, and defence against pathogens and herbivores. In recent years it has been postulated a possible contribution of peroxisomes to cellular signaling. In this volume an updated view of the capacity and function of peroxisomes from human, animal, fungal and plant origin as cell generators of different signal molecules involved in distinct processes of high physiological importance is presented.

Dedication

Preface

1. Peroxisome interactions and cross-talk with other subcellular compartments in animal cells; Michael Schrader, Sandra Grille, H. Dariush Fahimiand Markus Islinger

2. Peroxisomes in human health and disease: metabolic pathways, metabolite transport, interplay with other organelles and signal transduction; Ronald J.A. Wanders                            

3. Aging, age-related diseases and peroxisomes; Marc Fransen, Marcus Nordgren, Bo Wang, Oksana Apanasets and Paul P. Van Veldhoven 

4. Peroxisomes and the antiviral responses of mammalian cells; Charlotte Odendall and Jonathan C. Kagan 

5. Peroxisome proliferator-activated receptor-α signaling in hepatocarcinogenesis; Parimal Misra, Navin Viswakarmaand Janardan K. Reddy 

6. Involvement of human peroxisomes in biosynthesis and signaling of steroid and peptide hormones; Isabelle Weinhofer, Markus Kunze, Sonja Forss-Petterand Johannes Berger 

7. Peroxisome Ca2+ homeostasis in animal and plant cells; Alex Costa, Ilaria Drago, Michela Zottini, Paola Pizzoand Tullio Pozzan

8. The versatility of peroxisome function in filamentous fungi; Ida J. van der Kleiand Marten Veenhuis

9. Essential roles of peroxisomally produced and metabolized biomolecules in regulating yeast longevity; Adam Beachand Vladimir I. Titorenko 

10. Metabolite transporters of the plant peroxisomal membrane - known and unknown; Nicole Linkaand Frederica L. Theodoulou

11. Peroxisomes and photomorphogenesis; Navneet Kaur, Jiying Li, and Jianping Hu

12. Biosynthesis of vitamin K1 (phylloquinone) by plant peroxisomes and its integration into signaling molecule synthesis pathways; Sigrun Reumann                     

13. Role of peroxisomes as a source of reactive oxygen species (ROS) signaling molecules; Luisa M. Sandalio, María Rodríguez-Serrano, María C. Romero-Puertas and Luis A. del Río

14. Peroxisomes as a source of auxin signaling molecules; Gretchen M. Spiess and Bethany K. Zolman

15. Peroxisomes as cell generators of reactive nitrogen species (RNS) signal molecules; Francisco J. Corpas, Juan B. Barroso, José M Palmaand Luis A. del Río 

16. Role of plant peroxisomes in the production of jasmonic acid-based signals;José León

17. Role of plant peroxisomes in protection against herbivores; Mohammed Shabab

18. Function of Peroxisomes in Plant-Pathogen Interactions; Yasuyuki Kubo         

Index

Describes the central role played in cellular signaling by peroxisomes from different origins

Provides an up-to-date information on the function and metabolism of peroxisomes from human, animal, fungal and plant origin

Provides updated information on the metabolic interconnection and cross-talk of peroxisomes with other cell compartments

Describes the key cellular function played by peroxisomes as cell generators of important signaling molecules

Covers the role played by peroxisomes in human health, aging and disease