Radiotherapy and the Cancers of Children, Teenagers, and Young Adults
Radiotherapy in Practice Series

This new volume in the Radiotherapy in Practice series provides a comprehensive and evidence-based guide to radiotherapy in the management of children and young people with cancer. It explains the roles of the various modalities of treatment available, including image-guided and intensity modulated radiotherapy, brachytherapy, proton beam therapy, and molecular radiotherapy, and aids selection of the most appropriate technique in different situations. Each cancer type in children is explored, including diagnostic investigations, risk stratification, multi-modality approaches to treatment, and decision making with regard to radiotherapy. Specific guidance is given for the planning and prescription of radiotherapy for infants, children, and teenagers. The authors also identify the need for specialist paediatric radiotherapy service provision, and the wider requirements for radiotherapy in children, including consent, immobilisation, anaesthesia, multi-professional team working, and play specialist support. With over 75 colour illustrations, case histories to demonstrate the various approaches, and a carefully selected guide to further reading on each topic, this practical volume will be a valuable resource for physicians and trainees in radiotherapy and clinical oncology, and to nurses, radiographers and other allied health professionals who come into contact with young patients receiving radiotherapy. ABOUT THE SERIES Radiotherapy remains the major non-surgical treatment modality for the management of malignant disease. It is based on the application of the principles of applied physics, radiobiology, and tumour biology to clinical practice. Each volume in the series takes the reader through the basic principles of the use of ionizing radiation and then develops this by individual sites. This series of practical handbooks is aimed at physicians both training and practising in radiotherapy, as well as medical physics, dosimetrists, radiographers, and senior nurses.

Tom Boterberg graduated as an MD in 1994 at Ghent University. After one year of residency in radiation oncology, he worked for 4 years at the Laboratory of Experimental Cancer Research on the biology of the invasive and metastatic behaviour of breast cancer cells. He obtained his PhD in 2000. Afterwards he continued his training in radiation oncology and in 2001 he obtained his Board Certificate in Radiation Oncology. Since 2001 he works as a staff member at the Department of Radiation Oncology at Ghent University Hospital. He is especially interested in paediatricradiotherapy. He is actively involved in the radiotherapy committees of SIOPEN (neuroblastoma) and EpSSG (rhabdomyosarcoma). He is boardmember of SIOPE and chairs the QUARTET project on quality assurance in paediatric radiotherapy. He is author or co-author of over 100 articlesin peer-reviewed journals. His other interests are haematology, neuro-oncology, intra-operative brachytherapy and radioprotection. Karin Dieckmann graduated from the University of Hamburg,and was trained in Radiology and Radio-oncology at the University of Goettingen and at the Charité Berlin, all in Germany. Since 1994 she has worked at the Department of Radio-oncology of the Medical University Vienna and undertakes research in stereotactic radiosurgery and paediatric radiation oncology. She is especially interested in paediatic radiotherapy and is actively involved in the European Paediatric Hodgkin studies (EuroNetPhL C1 and C2), SIOPEN neuroblastoma study, and the European Brain Tumour Group. For many years she has been a faculty member of the ESTRO teaching courses,and is now chair of the ESTRO paediatric oncology teaching course. She is chair of the German Paediatric Radio-oncology Group (APRO). She is author and co-author of radiation oncology books, and of more than 150 articles in peer-reviewed journals. Mark Gaze qualified from Saint Bartholomew's Hospital, London. He trained in clinical oncology in Edinburgh and Glasgow a