Redirection of Th1 and Th2 Responses, Softcover reprint of the original 1st ed. 1999 Current Topics in Microbiology and Immunology Series, Vol. 238
Langue : Anglais
Coordonnateurs : Coffman Robert L., Romagnani Sergio
The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: - The mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production - The different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases - The prospects and strategies for therapeutic manipulation of Th1 and Th2 cells - The control of Th1 and Th2 responses by regulatory T cell subsets. The volume will give the reader a current view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.
List of Contents.- The Stability and Reversibility of Th1 and Th2 Populations.- T Helper Differentiation Proceeds Through Stat1-Dependent, Stat4-Dependent and Stat4-Independent Phases.- Redirecting Th2 Responses in Allergy.- Interleukin-12: Basic Principles and Clinical Applications.- Redirecting Th1 and Th2 Responses in Autoimmune Disease.- Manipulation of Th Responses by Oral Tolerance.
Date de parution : 01-2013
Ouvrage de 150 p.
15.5x23.5 cm
Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).
Prix indicatif 52,74 €
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Mots-clés :
T cell; autoimmune disease; autoimmunity; cell; cytokine; diseases; immune response; immunity; infectious disease
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