Description
Signaling by Toll-Like Receptors
Coordinator: Konat Gregory W.
Language: EnglishSubjects for Signaling by Toll-Like Receptors:
Keywords
TAK1 Activation; TRIF Dependent Pathway; GGA GGA; GE Healthcare Bio-Sciences; TLR Signaling; MyD88 Dependent Pathway; Anti-mouse TLR4; IKK Activation; Gap Junction; MyD88 Independent Pathway; TLR Ligand; Antibody Dilution Buffer; HEK293 Cell; FACS Buffer; Endogenous TLR Ligand; Gap Junction Channels; LPS Contamination; IFN Inducible Gene; TLR4 Deficient Mouse; T4 DNA Ligase; CDC42 Activity; HEK293T Cell; Mixed Glial Cultures; TLR Response; Tissue Tek OCT Compound
Publication date: 10-2019
· 15.6x23.4 cm · Paperback
Publication date: 06-2008
480 p. · 15.6x23.4 cm · Hardback
Description
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The discovery of toll-like receptors (TLRs) spurred the field of innate immunity into a renaissance after many years of neglect. Since then, TLR research has grown at an exponential rate. Taking an integrated methodological approach, Signaling by Toll-Like Receptors offers a comprehensive review of important techniques in molecular biology, cell biology, biochemistry, genetics, and immunology and their critical application to the study of toll-like receptor structure, biological function, and the intracellular signaling triggered by these receptors.
Assessing the Response of Cells to TLR Stimulation. TLR Ligands in Experimental Settings: Their Purity and Specificity. Analysis of TLR Expression, Regulation, and Signaling. Intracellular Trafficking of Toll-Like Receptors. The Role of Small RhoGTPases in TLR Signaling. Use of Engineered β-Lactamase Fragment Complementation to Detect the Associations of Toll-Like Receptors and Signaling Adaptors. Use of Toll-Like Receptor Chimeras to Dissect Mechanisms of Receptor Localization and Signaling. Engagement of Toll-Like Receptors Modulates Chemokine Receptor Signaling. Role of Toll-Like Receptor Signaling in Central Nervous System Infections. The Influence of Injury on Toll-Like Receptor Responses. Index.