Thrombosis and Thromboembolism

Written and edited by world-renowned leaders in the field!

Presents new directions for the prevention and treatment of arterial and venous cardiovascular thrombotic and thromboembolic diseases.

Updates contemporary thinking regarding low-molecular-weight-heparins (LMWH), platelet receptor antagonists, and direct thrombin inhibitors to manage acute coronary syndromes.

Evaluates contemporary strategies for anticoagulation and antiplatelet therapy to improve early clinical outcomes following percutaneous coronary intervention.

Offering diagnostic and management strategies to reduce morbidity and mortality from acute coronary syndromes and acute pulmonary embolism, Thrombosis and Thromboembolism is a superb reference for cardiologists, internists, primary care physicians, vascular medicine specialists, vascular surgeons, hematologists, pulmonologists and critical care physicians, cardiovascular surgeons, cardiac care nurses, and upper-level undergraduate, graduate, and medical school students in these disciplines.

Introduction
Samuel Z. Goldhaber and Paul M Ridker

Hypercoagulability

Inflammation and Arterial Thrombosis
David A. Morrow and Paul M Ridker
Homocysteine and Vascular Disease Risk
Peter W. F. Wilson
Antiphospholipid Antibody Syndrome
Mark A. Crowther and Jeffrey S. Ginsberg
The Epidemiology of Postmenopausal Hormone Therapy and Cardiovascular Disease
Francine Grodstein and Meir J. Stampfer

Clinical Pharmacology: Acute Coronary Syndromes

Low-Molecular-Weight Heparins and Direct Thrombin Inhibitors in Acute Coronary Syndromes
Robert P. Giugliano
Platelet Glycoprotein IIb/IIIa Inhibition in Acute Coronary Syndromes
Christopher P. Cannon
Aspirin, Ticlopidine, and Clopidogrel
Mark A. Creager
Clinical Accomplishments of ACE Inhibition Therapy: With and Without Aspirin
Marc A. Pfeffer

Diagnostic Laboratory and Catheter Interventions: Arterial

Detection of Peripheral Arterial Occlusion in the Vascular Laboratory
Marie Gerhard-Herman
Antithrombotic Therapy During Coronary Intervention
Jeffrey J. Popma and Arman T. Askari
Percutaneous Interventions for Obstructive Atherosclerotic Peripheral Arterial Disease
Joseph M. Garasic and Andrew C. Eisenhauer

Venous Thromboembolism

Venous Thromboembolism: Clinical Impact and Multifactorial Etiology
Samuel Z. Goldhaber
Integrated Diagnostic Approach to Venous Thromboembolism
Henri Bounameaux
The Management of Massive Pulmonary Embolism
Jeremy P. Feldman and Samuel Z. Goldhaber
Thrombolysis in Pulmonary Embolism
Samuel Z. Goldhaber
Optimal Duration of Anticoagulation Following Venous Thromboembolism Among Patients With and Without Inherited Thrombophilia
Gavin J. Blake and Paul M Ridker
The Expanded Role of an Interdisciplinary Anticoagulation Service
Kanella V. Tsilimingras and Kristen Hallisey

Catheter and Surgical Interventions: Venous

Interventional Venous Angiography