Description
Histamine and Histamine Receptors in Health and Disease, 1st ed. 2017
Handbook of Experimental Pharmacology Series, Vol. 241
Coordinators: Hattori Yuichi, Seifert Roland
Language: EnglishSubjects for Histamine and Histamine Receptors in Health and Disease:
Publication date: 08-2018
Support: Print on demand
Publication date: 06-2017
Support: Print on demand
Description
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Part 1: New Analytical tools.- Histamine and histamine receptors: State of the art.- Mass-spectrometric methods for the detection of histamine and histamine metabolites.- Fluorescent ligands and radioligands for the analysis of histamine receptors.- Molecular analysis of histamine receptors: Structural analysis of the histamine H1-receptor.- Molecular modelling approaches for the analysis of histamine receptors.- Cellular analysis of histamine receptors: Histamine release from human mast cells and basophils.- Histamine H2-receptor in blood cells: A suitable target for the treatment of acute myeloid leukemia.- Histamine H1-receptor-regulated gene expression and drug action of antihistamines.- Histamine metabolism and transport: Analysis of the role of histamine and genetically engineered mice in a human disease model.- Histamine clearance through polyspecific transporters in the brain.- Histamine decarboxylase deficiency as a cause for Tourette syndrome.- Histamine food poisoning.- Integrative role of histamine in major organ systems: Pharmacological implications: Regulation of the cardiovascular system by histamine.- Regulation of eating behavior by histamine.- Role of the histamine H3-receptor in the CNS.- Role of the histamine H4-receptor in bronchial asthma.- The histamine H4-receptor in pruritic skin disease.- Histamine in allergy and antihistamines.
Authors will cover hot topics in the field.
Update on last HEP volume on histamine published 25 years ago.
Unique topics are combined a in novel way
Includes supplementary material: sn.pub/extras
Includes supplementary material: sn.pub/extras