Advances in Triazole Chemistry

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Language: English

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264 p. · 15x22.8 cm · Paperback

Advances in Triazole Chemistry reviews the ever-widening scope of triazole chemistry. Triazole is an exceptional structural motif with a range of applications across scientific disciplines, including materials science, organocatalysis, agrochemicals, and medicinal chemistry. These many applications of different classes of triazoles have promoted the development of a range of synthetic strategies over the past few years, which are presented here along with recent and ecofriendly methods for the synthesis of all types of triazoles. The book also reviews the recent notable applications in chemical ligation, peptidomimetics, carbohydrate chemistry, nanotechnology, and polymer and materials science.

This comprehensive resource is ideal for researchers using triazoles in various disciplines, as well as chemists working in the pharmaceutical, polymer, and agrochemical industries.

  1. Introduction, classification, and synthesis of triazoles
  2. Triazoles as bioisosteres in medicinal chemistry: A recent update
  3. Site-specific incorporation of triazoles for functionalization of nucleotides, oligonucleotides, and nucleic acids
  4. Triazoles in synthesis and functionalization of polymers
  5. Triazole-based glycoconjugates
  6. Triazoles in nanotechnology
  7. Triazole-based plant growth-regulating agents: A recent update
  8. Triazoles in peptidomimetics: A recent update
  9. Triazoles in coordination complexes
  10. Triazoles in material sciences
Researchers using triazoles in various scientific disciplines including medicinal chemistry, polymer synthesis, nanotechnology, peptidomimetics, chemical ligation, agrochemicals, material science and carbohydrate chemistry. Secondary audience includes chemists working in industry including pharmaceutical, polymer and agrochemicals.
Tahir Farooq did his doctorate under the supervision of Dr. Bengt Erik Haug and Dr. Leiv K. Sydnes from the University of Bergen, Norway. During research work, he worked in the area of “click chemistry” for the synthesis of triazolic compounds. He followed Huisgen’s 1,3-dipolar cycloadditions using Cu-catalysis and Ru-catalysis approach to synthesize various 1,4- and 1,5-disubstituted 1,2,3-triazoles. Currently, Dr. Farooq is using the least-explored 1,2,3-triazoles as plant growth regulators and stress protectants, and is interested in exploring the role of 1,2,3-triazoles in abiotic stress management in crop plants.
  • Includes coverage of the role triazoles play in DNA synthesis
  • Features comprehensive information on 1,2,3-triazoles and 1,2,4-triazoles and their subclasses, synthesis, and applications
  • Serves as an ideal reference for researchers and chemists interested in using triazole chemistry for functionalization, modification, and development of target products