Flavin-Dependent Enzymes: Mechanisms, Structures and Applications

Director of collection: Tamanoi Fuyuhiko

Language: English

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566 p. · 15x22.8 cm · Hardback
The Enzymes, Volume 47, highlights new advances in the field, with this new volume presenting interesting chapters on The Multipurpose Family of Oxidases, Vanillyl alcohol oxidase, Choline oxidases, Aryl alcohol oxidase, D- and L-amino acid oxidases, Sugar oxidases, Phenolic Compounds hydroxylases, Baeyer-Villiger Monooxygenases, Flavin-dependent halogenases, Flavin-dependent dehalogenases, Styrene Monooxygenases, Bacterial luciferases, Cellobiose Dehydrogenases, Prenylated flavoenzymes, Ene-reductases, Flavoenzymes in Biocatalysis.

1. Overview of flavin-dependent enzymes

Panu Pimviriyakul and Pimchai Chaiyen

2. Flavoenzymes for biocatalysis

Mélanie Hall

3. The multipurpose family of flavoprotein oxidases

Marco Fraaije and Andrea Mattevi

4. Vanillyl alcohol oxidase

Tom A. Ewing, Gudrun Gygli, Marco W. Fraaije and Willem J.H. van Berkel

5. Porcine kidney D-amino acid oxidase-derived R-amine oxidases with new substrate specificities

Kazuyuki Yasukawa, Nobuhiro Kawahara, Fumihiro Motojima, Shogo Nakano and Yasuhisa Asano

6. Choline oxidases

Giovanni Gadda

7. Reaction mechanisms and applications of aryl-alcohol oxidase

Ana Serrano, Juan Carro and Angel T. Martínez

8. Structure and function relationships of sugar oxidases and their potential use in biocatalysis

Kanokkan Sriwaiyaphram, Pangrum Punthong, Jeerus Sucharitakul and Thanyaporn Wongnate

9. Baeyer-Villiger monooxygenases: From protein engineering to biocatalytic applications

Sandy Schmidt and Uwe T. Bornscheuer

10. Phenolic hydroxylases

Pirom Chenprakhon, Panu Pimviriyakul, Chanakan Tongsook and Pimchai Chaiyen

11. Structures, mechanisms and applications of flavin-dependent halogenases

Aisaraphon Phintha, Kridsadakorn Prakinee and Pimchai Chaiyen

12. Flavin-dependent dehalogenases

Panu Pimviriyakul and Pimchai Chaiyen

13. Styrene monooxygenases, indole monooxygenases and related flavoproteins applied in bioremediation and biocatalysis

Dirk Tischler, Antje Kumpf, Daniel Eggerichs and Thomas Heine

14. Bacterial luciferase: Molecular mechanisms and applications

Ruchanok Tinikul, Paweenapon Chunthaboon, Jittima Phonbuppha and Tanakan Paladkong

15. Cellobiose dehydrogenase

Florian Csarman, Lena Wohlschlager and Roland Ludwig

16. Thermal, electrochemical and photochemical reactions involving catalytically versatile ene reductase enzymes

Helen S. Toogood and Nigel S. Scrutton

17. Biochemistry of prenylated-FMN enzymes

Annica Saaret, Arune Balaikaite and David Leys

Specialists in the field of Enzymes
Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997. Since 1996, he has been a Director of Signal Transduction Program Area at Jonsson Comprehensive Cancer Center. Dr. Tamanoi earned his B.S. and M.S. in Biochemistry at the University of Tokyo. He received PhD in Molecular Biology at Nagoya University in 1977. He was a postdoctoral fellow at Harvard Medical School, where he worked on bacteriophage DNA replication. From 1980 to 1985, he was a senior staff investigator at Cold Spring Harbor Laboratory, where he worked on adenovirus DNA replication. From 1985 to 1993, he was an Assistant Professor and then Associate Professor at the University of Chicago, where he initiated studies on lipid modification of the Ras family proteins. His laboratory research centers on signal transduction and signal transduction inhibitors. He is currently exploring ways to deliver signal transduction inhibitors using nanoparticles.
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